advanced ? | example input
  • Species
    • Species

  • Modification ?
  • Function ?
  • Genomic location?
    • Chromosome ?
    • Position on chromosome ?
  • Minum number of ?
    • N termini
    • C termini


  • TopFIND is the first public knowledgebase and analysis resource for protein termini and protease processing

  • More than 290,000 N- and C-termini and more than 33,000 cleavages listed

  • Covers H. sapiens, M. musculus, R. norvegicus, S. cerevisiae, A. thaliana and E. coli


  • Integration of protein termini & function with proteolytic processing, alternative transcription & translation

  • Displays proteases and substrates within their protease web including detailed evidence information

  • TopFINDer automates analysis and functional annotation of proteomics-derived termini sets

  • PathFINDer identifies indirect protease-substrate connections for the evaluation of complex processes


  • Submit your N- or C-termini datasets

  • Contribute information on protein cleavages

  • Provide detailed experimental description, sample information and raw data