O08736: CASPC (Mouse)

Protein names
  • CASPC
Gene names Casp12
Organism Mus musculus
Protease Family C14 (MEROPS)
Protease ID C14.013 (MEROPS)
Chromosome 9

Sequence

        10         20         30         40         50         60 
MAARRTHERD PIYKIKGLAK DMLDGVFDDL VEKNVLNGDE LLKIGESASF ILNKAENLVE 
        70         80         90        100        110        120 
NFLEKTDMAG KIFAGHIANS QEQLSLQFSN DEDDGPQKIC TPSSPSESKR KVEDDEMEVN 
       130        140        150        160        170        180 
AGLAHESHLM LTAPHGLQSS EVQDTLKLCP RDQFCKIKTE RAKEIYPVME KEGRTRLALI 
       190        200        210        220        230        240 
ICNKKFDYLF DRDNADTDIL NMQELLENLG YSVVLKENLT AQEMETELMQ FAGRPEHQSS 
       250        260        270        280        290        300 
DSTFLVFMSH GILEGICGVK HRNKKPDVLH DDTIFKIFNN SNCRSLRNKP KILIMQACRG 
       310        320        330        340        350        360 
RYNGTIWVST NKGIATADTD EERVLSCKWN NSITKAHVET DFIAFKSSTP HNISWKVGKT 
       370        380        390        400        410    
GSLFISKLID CFKKYCWCYH LEEIFRKVQH SFEVPGELTQ MPTIERVSMT RYFYLFPGN

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:

 
 
N-termini:

NNNNNN
 
C-termini:
CCCCCC
 
Cleavage sites:
     
 
Features:
 
 
 
Binding & active sites:
  
 
(NDEDD(94)|(95)GPQKI)
94,419

Caspase-7 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Bredesen DE Rao RV et al.:Coupling endoplasmic reticulum ... (C14.004) unknown yes

Targeted features: ?

94,419,419,0 CHAIN - Caspase-12. (0|419)
 
(HLMLT(132)|(133)APHGL)
132,419

Calpain-2 catalytic subunit (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Yuan J Nakagawa T et al.:Cross-talk between two cysteine... (C02.002) unknown yes

Targeted features: ?

132,419,419,0 CHAIN - Caspase-12. (0|419)
 
(FCKIK(158)|(159)TERAK)
158,419

Calpain-2 catalytic subunit (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Yuan J Nakagawa T et al.:Cross-talk between two cysteine... (C02.002) unknown yes

Targeted features: ?

158,419,419,0 CHAIN - Caspase-12. (0|419)
 
(IATAD(318)|(319)TDEER)
318,419

CASPC (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Momoi T Fujita E et al.:Caspase-12 processing and fragm... (C14.013) unknown yes

Targeted features: ?

318,419,419,0 CHAIN - Caspase-12. (0|419)
 
(HVETD(341)|(342)FIAFK)
341,419

CASPC (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Bredesen DE Rao RV et al.:Coupling endoplasmic reticulum ... (C14.004) unknown yes

Targeted features: ?

341,419,419,0 CHAIN - Caspase-12. (0|419)
 
unknown-0NMAARR...
0,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,419,419,0 CHAIN - Caspase-12. (0|419)
 
unknown-95GPQKIC...
95,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28531 indirect unknown (unknown)
 
unknown-133APHGLQ...
133,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28315 indirect unknown (unknown)
 
unknown-159TERAKE...
159,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28316 indirect unknown (unknown)
 
unknown-319TDEERV...
319,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28619 indirect unknown (unknown)
 
unknown-342FIAFKS...
342,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28620 indirect unknown (unknown)
 

Protein C-Termini [export]

...NDEDD94-unknown
94,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28531 indirect unknown (unknown)
 
...HLMLT132-unknown
132,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28315 indirect unknown (unknown)
 
...FCKIK158-unknown
158,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28316 indirect unknown (unknown)
 
...IATAD318-unknown
318,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28619 indirect unknown (unknown)
 
...HVETD341-unknown
341,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28620 indirect unknown (unknown)
 
...LFPGN419-unknown
419,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

419,419,419,0 CHAIN - Caspase-12. (0|419)
 
318 (ATAD.|.TDEE)
318,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Momoi T Fujita E et al.:Caspase-12 processing and fragm... (C14.013) unknown yes
 
341 (VETD.|.FIAF)
341,419

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Bredesen DE Rao RV et al.:Coupling endoplasmic reticulum ... (C14.004) unknown yes
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?