O95336: 6-phosphogluconolactonase (Human)

Protein names
  • 6-phosphogluconolactonase (6PGL)
  • 6PGL
Gene names PGLS
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 19

Sequence

        10         20         30         40         50         60 
MAAPAPGLIS VFSSSQELGA ALAQLVAQRA ACCLAGARAR FALGLSGGSL VSMLARELPA 
        70         80         90        100        110        120 
AVAPAGPASL ARWTLGFCDE RLVPFDHAES TYGLYRTHLL SRLPIPESQV ITINPELPVE 
       130        140        150        160        170        180 
EAAEDYAKKL RQAFQGDSIP VFDLLILGVG PDGHTCSLFP DHPLLQEREK IVAPISDSPK 
       190        200        210        220        230        240 
PPPQRVTLTL PVLNAARTVI FVATGEGKAA VLKRILEDQE ENPLPAALVQ PHTGKLCWFL 
       250    
DEAAARLLTV PFEKHSTL

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
Chains:
 
 
N-termini:

N
NNN
 
C-termini:
CCC
 
Cleavage sites:
 
 
Features:
 
 
Modifications:
  
 
(VAPIS(176)|(177)DSPKP)
176,258

Meprin A subunit beta (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Becker-Pauly C et al.:Proteomic analyses reveal an ac... (M12.002) unknown none

Targeted features: ?

176,258,258,2 CHAIN - 6-phosphogluconolactonase. (2|258)
 
unknown-1MAAPAP...
1,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,258,1,1 INIT_MET - Removed. (1|1)
 
acetylation-2AAPAPG...
2,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Overall Laboratory Lange_Huesgen_et_al-RBC direct yes 0.88 (PeptideProphet probability)

Affected feature boundaries: ?

2,258,2,2 MOD_RES - N-acetylalanine. (2|2)
2,258,258,2 CHAIN - 6-phosphogluconolactonase. (2|258)
 
unknown-65AGPASL...
65,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000471951 unknown unknown (unknown)
 
unknown-177DSPKPP...
177,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC18329 indirect unknown (unknown)
 

Protein C-Termini [export]

...VAPIS176-unknown
176,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC18329 indirect unknown (unknown)
 
...TGEGK208-unknown
208,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000472345 unknown unknown (unknown)
 
...KHSTL258-unknown
258,258

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

258,258,258,2 CHAIN - 6-phosphogluconolactonase. (2|258)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct
  • indirect

Physiological relevance ?

  • none
  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • PeptideProphet probability

Experimental system ?

Certainty of Protease assignment ?

  • unknown
  • IV proteolytic system present and active

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?