P07359: Platelet glycoprotein Ib alpha chain (Human)

Protein names
  • Platelet glycoprotein Ib alpha chain (GP-Ib alpha)
  • Antigen CD42b-alpha (GP-Ib alpha)
  • GP1BA
Gene names GP1BA
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 17

Sequence

        10         20         30         40         50         60 
MPLLLLLLLL PSPLHPHPIC EVSKVASHLE VNCDKRNLTA LPPDLPKDTT ILHLSENLLY 
        70         80         90        100        110        120 
TFSLATLMPY TRLTQLNLDR CELTKLQVDG TLPVLGTLDL SHNQLQSLPL LGQTLPALTV 
       130        140        150        160        170        180 
LDVSFNRLTS LPLGALRGLG ELQELYLKGN ELKTLPPGLL TPTPKLEKLS LANNNLTELP 
       190        200        210        220        230        240 
AGLLNGLENL DTLLLQENSL YTIPKGFFGS HLLPFAFLHG NPWLCNCEIL YFRRWLQDNA 
       250        260        270        280        290        300 
ENVYVWKQGV DVKAMTSNVA SVQCDNSDKF PVYKYPGKGC PTLGDEGDTD LYDYYPEEDT 
       310        320        330        340        350        360 
EGDKVRATRT VVKFPTKAHT TPWGLFYSWS TASLDSQMPS SLHPTQESTK EQTTFPPRWT 
       370        380        390        400        410        420 
PNFTLHMESI TFSKTPKSTT EPTPSPTTSE PVPEPAPNMT TLEPTPSPTT PEPTSEPAPS 
       430        440        450        460        470        480 
PTTPEPTSEP APSPTTPEPT SEPAPSPTTP EPTPIPTIAT SPTILVSATS LITPKSTFLT 
       490        500        510        520        530        540 
TTKPVSLLES TKKTIPELDQ PPKLRGVLQG HLESSRNDPF LHPDFCCLLP LGFYVLGLFW 
       550        560        570        580        590        600 
LLFASVVLIL LLSWVGHVKP QALDSGQGAA LTTATQTTHL ELQRGRQVTV PRAWLLFLRG 
       610        620        630        640        650    
SLPTFRSSLF LWVRPNGRVG PLVAGRRPSA LSQGRGQDLL STVSIRYSGH SL

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
500
600
Chains:
 
 
 
N-termini:
NN
NN
 
C-termini:

CC
CCC
 
Cleavage sites:
   
 
Features:
   
 
Modifications:
     
 
(GDTDL(291)|(292)YDYYP)
291,652

Cathepsin G (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Chignard M Pidard D et al.:Neutrophil proteinase cathepsin... (S01.133) unknown yes

Targeted features: ?

291,652,531,17 TOPO_DOM - Extracellular (Potential). (17|531)
291,652,652,17 CHAIN - Platelet glycoprotein Ib alpha chain. (17|652)

Affected feature boundaries: ?

291,652,292,292 MOD_RES - Sulfotyrosine. (292|292)
 
(DTDLY(292)|(293)DYYPE)
292,652

Cathepsin G (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Berndt MC Gardiner EE et al.:Regulation of P-selectin bindin... (S01.133) unknown yes

Targeted features: ?

292,652,531,17 TOPO_DOM - Extracellular (Potential). (17|531)
292,652,652,17 CHAIN - Platelet glycoprotein Ib alpha chain. (17|652)

Affected feature boundaries: ?

292,652,292,292 MOD_RES - Sulfotyrosine. (292|292)
292,652,292,292 MOD_RES - Sulfotyrosine. (292|292)
 
(TRTVV(312)|(313)KFPTK)
312,652

Cathepsin G (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Chignard M Pidard D et al.:Neutrophil proteinase cathepsin... (S01.133) unknown yes

Targeted features: ?

312,652,531,17 TOPO_DOM - Extracellular (Potential). (17|531)
312,652,652,17 CHAIN - Platelet glycoprotein Ib alpha chain. (17|652)
 
unknown-17HPICEV...
17,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

17,652,531,17 TOPO_DOM - Extracellular (Potential). (17|531)
17,652,652,17 CHAIN - Platelet glycoprotein Ib alpha chain. (17|652)
17,652,0,17 CHAIN - Glycocalicin. (17|0)
17,652,47,17 DOMAIN - LRRNT. (17|47)
 
unknown-292YDYYPE...
292,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4777 indirect unknown (unknown)

Affected feature boundaries: ?

292,652,292,292 MOD_RES - Sulfotyrosine. (292|292)
 
unknown-293DYYPEE...
293,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4778 indirect unknown (unknown)
 
unknown-313KFPTKA...
313,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4779 indirect unknown (unknown)
 

Protein C-Termini [export]

...SGHSL0-unknown
0,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,652,0,17 CHAIN - Glycocalicin. (17|0)
 
...GDTDL291-unknown
291,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4777 indirect unknown (unknown)
 
...DTDLY292-unknown
292,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4778 indirect unknown (unknown)

Affected feature boundaries: ?

292,652,292,292 MOD_RES - Sulfotyrosine. (292|292)
 
...TRTVV312-unknown
312,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC4779 indirect unknown (unknown)
 
...SGHSL652-unknown
652,652

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

652,652,652,553 TOPO_DOM - Cytoplasmic (Potential). (553|652)
652,652,652,17 CHAIN - Platelet glycoprotein Ib alpha chain. (17|652)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?