P09238: Stromelysin-2 (Human)

Protein names
  • Stromelysin-2 (SL-2)
  • Matrix metalloproteinase-10 Short=MMP-10 (SL-2)
  • Transin-2 (SL-2)
  • MMP10
Gene names MMP10 (STMY2)
Organism Homo sapiens
Protease Family M10 (MEROPS)
Protease ID M10.006 (MEROPS)
Chromosome 11

Sequence

        10         20         30         40         50         60 
MMHLAFLVLL CLPVCSAYPL SGAAKEEDSN KDLAQQYLEK YYNLEKDVKQ FRRKDSNLIV 
        70         80         90        100        110        120 
KKIQGMQKFL GLEVTGKLDT DTLEVMRKPR CGVPDVGHFS SFPGMPKWRK THLTYRIVNY 
       130        140        150        160        170        180 
TPDLPRDAVD SAIEKALKVW EEVTPLTFSR LYEGEADIMI SFAVKEHGDF YSFDGPGHSL 
       190        200        210        220        230        240 
AHAYPPGPGL YGDIHFDDDE KWTEDASGTN LFLVAAHELG HSLGLFHSAN TEALMYPLYN 
       250        260        270        280        290        300 
SFTELAQFRL SQDDVNGIQS LYGPPPASTE EPLVPTKSVP SGSEMPAKCD PALSFDAIST 
       310        320        330        340        350        360 
LRGEYLFFKD RYFWRRSHWN PEPEFHLISA FWPSLPSYLD AAYEVNSRDT VFIFKGNEFW 
       370        380        390        400        410        420 
AIRGNEVQAG YPRGIHTLGF PPTIRKIDAA VSDKEKKKTY FFAADKYWRF DENSQSMEQG 
       430        440        450        460        470    
FPRLIADDFP GVEPKVDAVL QAFGFFYFFS GSSQFEFDPN ARMVTHILKS NSWLHC

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
N-termini:
NN
 
C-termini:
C
 
Features:
  
 
 
Binding & active sites:
         
 
Sequence variations:
        
 
unknown-18YPLSGA...
18,476

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

18,476,98,18 PROPEP - Activation peptide. (18|98)
 
unknown-99FSSFPG...
99,476

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

99,476,476,99 CHAIN - Stromelysin-2. (99|476)
 

Protein C-Termini [export]

...SWLHC476-unknown
476,476

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

476,476,476,289 DISULFID - By similarity. (289|476)
476,476,476,99 CHAIN - Stromelysin-2. (99|476)
476,476,476,433 REPEAT - Hemopexin 4. (433|476)
 
31 (RAIH.|.IQAE)
31,354

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Roughley PJ Nguyen Q et al.:Matrix metalloproteinases cleav... (M10.006) unknown yes
 
40 (GPHL.|.LVEA)
40,354

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Roughley PJ Nguyen Q et al.:Matrix metalloproteinases cleav... (M10.006) unknown yes
 
98 (DSGG.|.FMLT)
98,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Tschesche H Knauper V et al.:Activation of human neutrophil ... (M10.006) unknown yes
 
106 (DLGR.|.FQTF)
106,707

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Okada Y Nakamura H et al.:Activation of the precursor of ... (M10.006) unknown yes
 
111 ()
111,171

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19931 indirect unknown
 
169 ()
169,171

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19934 indirect unknown
 
137 ()
137,197

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19931 indirect unknown
 
195 ()
195,197

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19934 indirect unknown
 
158 ()
158,160

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19934 indirect unknown
 
184 ()
184,186

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19934 indirect unknown
 
244 (RGLS.|.LSRF)
244,304

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Strongin AY Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) unknown yes
 
302 (SPMA.|.RR)
302,304

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Strongin AY Shiryaev SA et al.:Matrix metalloproteinase proteo... (M10.006) unknown yes
 
360 (IPEN.|.FFGV)
360,2415

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Hamilton JA Fosang AJ et al.:Cleavage of cartilage proteogly... (M10.006) unknown yes
 
360 ()
360,2316

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19942 indirect unknown
 
360 ()
360,2377

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC19942 indirect unknown
 
402 (GGIG.|.QLTA)
402,3142

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Ellerby LM Miller JP et al.:Matrix metalloproteinases are m... (M10.006) unknown yes
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?