P09440: C-1-tetrahydrofolate synthase, mitochondrial (strain ATCC 204508 / S288c) (Baker's yeast)

Protein names
  • C-1-tetrahydrofolate synthase, mitochondrial (C1-THF synthase)
  • Methylenetetrahydrofolate dehydrogenase EC=1.5.1.5 Includes: (C1-THF synthase)
  • Methenyltetrahydrofolate cyclohydrolase EC=3.5.4.9 Includes: (C1-THF synthase)
  • Formyltetrahydrofolate synthetase EC=6.3.4.3 Flags: Precursor (C1-THF synthase)
  • C1TM
Gene names MIS1
Organism Saccharomyces cerevisiae
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome II

Sequence

        10         20         30         40         50         60 
MLSRLSLLSN SRAFQQARWR IYRLKVSPTV HASQYHILSG RKLAQSIREK ANDEIQAIKL 
        70         80         90        100        110        120 
KHPNFKPTLK IIQVGARPDS STYVRMKLKA SKDSNVDCII EKLPAEITEV ELLKKISDIN 
       130        140        150        160        170        180 
DDDSIHGLLI QLPLPRHLDE TTITNAVDFK KDVDGFHRYN AGELAKKGGK PYFIPCTPYG 
       190        200        210        220        230        240 
CMKLLEEAHV KLDGKNAVVL GRSSIVGNPI ASLLKNANAT VTVCHSHTRN IAEVVSQADI 
       250        260        270        280        290        300 
VIAACGIPQY VKSDWIKEGA VVIDVGINYV PDISKKSGQK LVGDVDFDSV KEKTSYITPV 
       310        320        330        340        350        360 
PGGVGPMTVA MLVSNVLLAA KRQFVESEKL PVIKPLPLHL ESPVPSDIDI SRAQSPKHIK 
       370        380        390        400        410        420 
QVAEELGIHS HELELYGHYK AKISPNIFKR LESRENGKYV LVAGITPTPL GEGKSTTTMG 
       430        440        450        460        470        480 
LVQALSAHLG KPSIANVRQP SLGPTLGVKG GAAGGGYAQV IPMDEFNLHL TGDIHAISAA 
       490        500        510        520        530        540 
NNLLAAAIDT RMFHEATQKN DSTFYKRLVP RKKGIRKFTP SMQRRLKRLD IEKEDPDALT 
       550        560        570        580        590        600 
PEEVKRFARL NINPDTITIR RVVDINDRML RQITIGEAAT EKGFTRTTGF DITVASELMA 
       610        620        630        640        650        660 
ILALSKSLHE MKERIGRMVI GADYDNKPVT VEDIGCTGAL TALLRDAIKP NLMQTLEGTP 
       670        680        690        700        710        720 
VMVHAGPFAN ISIGASSVIA DLMALKLVGS EKNPLNDKNI HEPGYVVTEA GFDFAMGGER 
       730        740        750        760        770        780 
FFDIKCRSSG LVPDAVVLVA TVRALKSHGG APNVKPGQSL PKEYTEENID FVAKGVSNLV 
       790        800        810        820        830        840 
KQIENIKTFG IPVVVAINRF ETDSQAEIEV IKKAALNAGA SHAVTSNHWM EGGKGAVELA 
       850        860        870        880        890        900 
HAVVDATKEP KNFNFLYDVN SSIEDKLTSI VQKMYGGAKI EVSPEAQKKI DTYKKQGFGN 
       910        920        930        940        950        960 
LPICIAKTQY SLSHDPSLKG VPRGFTFPIR DVRASIGAGY LYALAAEIQT IPGLSTYAGY 
       970    
MAVEVDDDGE IEGLF

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
N-termini:
NN
 
C-termini:
C
 
Features:
  
    
 
Binding & active sites:
   
 
unknown-10NSRAFQ...
10,975

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... unknown unknown (unknown)
 
unknown-35YHILSG...
35,975

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Voegtle FN. et al.: Global Analysis of the Mitochondrial N-Proteome... unknown unknown (unknown)

Affected feature boundaries: ?

35,975,343,35 REGION - Methylenetetrahydrofolate dehydrogenase and cyclohydrolase. (35|343)
35,975,975,35 CHAIN - C-1-tetrahydrofolate synthase, mitochondrial. (35|975)
 

Protein C-Termini [export]

...IEGLF975-unknown
975,975

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

975,975,975,344 REGION - Formyltetrahydrofolate synthetase. (344|975)
975,975,975,35 CHAIN - C-1-tetrahydrofolate synthase, mitochondrial. (35|975)
 
Filter by evidence: ?

Directness ?

  • unknown

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?