P09603: Macrophage colony-stimulating factor 1 (Human)

Protein names
  • Macrophage colony-stimulating factor 1 (CSF-1)
  • Lanimostim (CSF-1)
  • CSF1
Gene names CSF1
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 1

Isoforms

  • Isoform 2 of Macrophage colony-stimulating factor 1 (P09603-2): sequence view | extended view
  • Isoform 3 of Macrophage colony-stimulating factor 1 (P09603-3): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MTAPGAAGRC PPTTWLGSLL LLVCLLASRS ITEEVSEYCS HMIGSGHLQS LQRLIDSQME 
        70         80         90        100        110        120 
TSCQITFEFV DQEQLKDPVC YLKKAFLLVQ DIMEDTMRFR DNTPNAIAIV QLQELSLRLK 
       130        140        150        160        170        180 
SCFTKDYEEH DKACVRTFYE TPLQLLEKVK NVFNETKNLL DKDWNIFSKN CNNSFAECSS 
       190        200        210        220        230        240 
QDVVTKPDCN CLYPKAIPSS DPASVSPHQP LAPSMAPVAG LTWEDSEGTE GSSLLPGEQP 
       250        260        270        280        290        300 
LHTVDPGSAK QRPPRSTCQS FEPPETPVVK DSTIGGSPQP RPSVGAFNPG MEDILDSAMG 
       310        320        330        340        350        360 
TNWVPEEASG EASEIPVPQG TELSPSRPGG GSMQTEPARP SNFLSASSPL PASAKGQQPA 
       370        380        390        400        410        420 
DVTGTALPRV GPVRPTGQDW NHTPQKTDHP SALLRDPPEP GSPRISSLRP QGLSNPSTLS 
       430        440        450        460        470        480 
AQPQLSRSHS SGSVLPLGEL EGRRSTRDRR SPAEPEGGPA SEGAARPLPR FNSVPLTDTG 
       490        500        510        520        530        540 
HERQSEGSFS PQLQESVFHL LVPSVILVLL AVGGLLFYRW RRRSHQEPQR ADSPLEQPEG 
       550    
SPLTQDDRQV ELPV

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
 
N-termini:

NN
 
C-termini:

CC
 
Features:
  
 
unknown-1MTAPGA...
1,554

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt71851 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt71852 indirect unknown (unknown)

Affected feature boundaries: ?

1,554,32,1 SIGNAL - (1|32)
 
unknown-33EEVSEY...
33,554

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt115049 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt115050 indirect unknown (unknown)

Affected feature boundaries: ?

33,554,496,33 TOPO_DOM - Lumenal (Potential). (33|496)
33,554,554,33 CHAIN - Macrophage colony-stimulating factor 1. (33|554)
33,554,0,33 CHAIN - Processed macrophage colony-stimulating factor 1. (33|0)
 

Protein C-Termini [export]

...VELPV0-unknown
0,554

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,554,0,33 CHAIN - Processed macrophage colony-stimulating factor 1. (33|0)
 
...VELPV554-unknown
554,554

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt67470 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt67469 indirect unknown (unknown)

Affected feature boundaries: ?

554,554,554,518 TOPO_DOM - Cytoplasmic (Potential). (518|554)
554,554,554,33 CHAIN - Macrophage colony-stimulating factor 1. (33|554)
554,554,554,489 MUTAGEN - Missing: Produces biologically active protein which is secreted. (489|554)
 
Filter by evidence: ?

Directness ?

  • indirect
  • unknown

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?