P10126: Elongation factor 1-alpha 1 (Mouse)

Protein names
  • Elongation factor 1-alpha 1 (EF-1-alpha-1)
  • Elongation factor Tu Short=EF-Tu (EF-1-alpha-1)
  • Eukaryotic elongation factor 1 A-1 Short=eEF1A-1 (EF-1-alpha-1)
  • EF1A1
Gene names Eef1a1 (Eef1a)
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 9

Sequence

        10         20         30         40         50         60 
MGKEKTHINI VVIGHVDSGK STTTGHLIYK CGGIDKRTIE KFEKEAAEMG KGSFKYAWVL 
        70         80         90        100        110        120 
DKLKAERERG ITIDISLWKF ETSKYYVTII DAPGHRDFIK NMITGTSQAD CAVLIVAAGV 
       130        140        150        160        170        180 
GEFEAGISKN GQTREHALLA YTLGVKQLIV GVNKMDSTEP PYSQKRYEEI VKEVSTYIKK 
       190        200        210        220        230        240 
IGYNPDTVAF VPISGWNGDN MLEPSANMPW FKGWKVTRKD GSASGTTLLE ALDCILPPTR 
       250        260        270        280        290        300 
PTDKPLRLPL QDVYKIGGIG TVPVGRVETG VLKPGMVVTF APVNVTTEVK SVEMHHEALS 
       310        320        330        340        350        360 
EALPGDNVGF NVKNVSVKDV RRGNVAGDSK NDPPMEAAGF TAQVIILNHP GQISAGYAPV 
       370        380        390        400        410        420 
LDCHTAHIAC KFAELKEKID RRSGKKLEDG PKFLKSGDAA IVDMVPGKPM CVESFSDYPP 
       430        440        450        460    
LGRFAVRDMR QTVAVGVIKA VDKKAAGAGK VTKSAQKAQK AK

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
Binding & active sites:
   
 
Sequence variations:
          
   
 
(FKYAW(58)|(59)VLDKL)
58,462

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> EF1A1_MOUSE @58 unknown yes

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> EF1A1_MOUSE @58 unknown yes

Targeted features: ?

58,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(IDISL(77)|(78)WKFET)
77,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

77,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)

Affected feature boundaries: ?

77,462,78,77 CONFLICT - LW -> QR (in Ref. 2; CAA31957). (77|78)
 
(DCAVL(114)|(115)IVAAG)
114,462

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> EF1A1_MOUSE @114 unknown yes

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> EF1A1_MOUSE @114 unknown yes

Targeted features: ?

114,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(AGVGE(122)|(123)FEAGI)
122,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

122,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(LGVKQ(147)|(148)LIVGV)
147,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> EF1A1_MOUSE @147 unknown none

Targeted features: ?

147,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(GVKQL(148)|(149)IVGVN)
148,462

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> EF1A1_MOUSE @148 unknown yes

Targeted features: ?

148,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(LPLQD(252)|(253)VYKIG)
252,462

Granzyme B(G,H) (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Gevaert K Van Damme P et al.:Analysis of protein processing ... (S01.010) unknown yes

Targeted features: ?

252,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(LQDVY(254)|(255)KIGGI)
254,462

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> EF1A1_MOUSE @254 unknown yes

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> EF1A1_MOUSE @254 unknown yes

Targeted features: ?

254,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(VPVGR(266)|(267)VETGV)
266,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> EF1A1_MOUSE @266 unknown none

Targeted features: ?

266,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(FAPVN(284)|(285)VTTEV)
284,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> EF1A1_MOUSE @284 unknown none

Targeted features: ?

284,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(NHPGQ(352)|(353)ISAGY)
352,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> EF1A1_MOUSE @352 unknown none

Targeted features: ?

352,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(DGPKF(393)|(394)LKSGD)
393,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

Matrix metalloproteinase-9 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

Targeted features: ?

393,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)

Affected feature boundaries: ?

393,462,392,392 MOD_RES - N6-acetyllysine; alternate. (392|392)
393,462,392,392 MOD_RES - N6-succinyllysine; alternate. (392|392)
 
(LKSGD(398)|(399)AAIVD)
398,462

Granzyme B(G,H) (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Gevaert K Van Damme P et al.:Analysis of protein processing ... (S01.010) unknown yes

Targeted features: ?

398,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(SGDAA(400)|(401)IVDMV)
400,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

400,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(PMCVE(413)|(414)SFSDY)
413,462

Granzyme B(G,H) (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Gevaert K Van Damme P et al.:Analysis of protein processing ... (S01.010) unknown yes

Targeted features: ?

413,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(MCVES(414)|(415)FSDYP)
414,462

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> EF1A1_MOUSE @414 unknown yes

Targeted features: ?

414,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
(VAVGV(437)|(438)IKAVD)
437,462

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> EF1A1_MOUSE @437 unknown none

Targeted features: ?

437,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
unknown-1MGKEKT...
1,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
unknown-9NIVVIG...
9,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
 
unknown-32GGIDKR...
32,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
 
unknown-59VLDKLK...
59,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28745 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29682 indirect unknown (unknown)
 
unknown-78WKFETS...
78,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33305 indirect unknown (unknown)
 
unknown-115IVAAGV...
115,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28746 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29683 indirect unknown (unknown)
 
unknown-123FEAGIS...
123,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33306 indirect unknown (unknown)
 
unknown-134REHALL...
134,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
 
unknown-148LIVGVN...
148,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33307 indirect unknown (unknown)
 
unknown-149IVGVNK...
149,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28747 indirect unknown (unknown)
 
acetylation-219KDGSAS...
219,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall CM. Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... direct likely 0.0 (unknown)
 
unknown-253VYKIGG...
253,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32306 indirect unknown (unknown)
 
unknown-255KIGGIG...
255,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28748 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29684 indirect unknown (unknown)
 
unknown-267VETGVL...
267,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33308 indirect unknown (unknown)
 
unknown-285VTTEVK...
285,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33309 indirect unknown (unknown)
 
unknown-353ISAGYA...
353,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33310 indirect unknown (unknown)
 
unknown-394LKSGDA...
394,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33311 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC34619 indirect unknown (unknown)
 
unknown-399AAIVDM...
399,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32307 indirect unknown (unknown)
 
unknown-401IVDMVP...
401,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33312 indirect unknown (unknown)
 
unknown-412VESFSD...
412,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall CM. Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... direct likely 0.0 (unknown)
 
unknown-414SFSDYP...
414,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32308 indirect unknown (unknown)
 
unknown-415FSDYPP...
415,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28749 indirect unknown (unknown)
 
unknown-438IKAVDK...
438,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33313 indirect unknown (unknown)
 

Protein C-Termini [export]

...FKYAW58-unknown
58,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28745 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29682 indirect unknown (unknown)
 
...IDISL77-unknown
77,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33305 indirect unknown (unknown)
 
...DCAVL114-unknown
114,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28746 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29683 indirect unknown (unknown)
 
...AGVGE122-unknown
122,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33306 indirect unknown (unknown)
 
...LGVKQ147-unknown
147,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33307 indirect unknown (unknown)
 
...GVKQL148-unknown
148,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28747 indirect unknown (unknown)
 
...GYNPD186-unknown
186,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000116821 unknown unknown (unknown)
 
...PLRLP249-unknown
249,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000120438 unknown unknown (unknown)
 
...LPLQD252-unknown
252,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32306 indirect unknown (unknown)
 
...LQDVY254-unknown
254,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28748 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29684 indirect unknown (unknown)
 
...VPVGR266-unknown
266,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33308 indirect unknown (unknown)
 
...FAPVN284-unknown
284,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33309 indirect unknown (unknown)
 
...NHPGQ352-unknown
352,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33310 indirect unknown (unknown)
 
...DGPKF393-unknown
393,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33311 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC34619 indirect unknown (unknown)
 
...LKSGD398-unknown
398,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32307 indirect unknown (unknown)
 
...SGDAA400-unknown
400,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33312 indirect unknown (unknown)
 
...PMCVE413-unknown
413,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC32308 indirect unknown (unknown)
 
...MCVES414-unknown
414,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28749 indirect unknown (unknown)
 
...VAVGV437-unknown
437,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33313 indirect unknown (unknown)
 
...AQKAK462-unknown
462,462

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

462,462,462,1 CHAIN - Elongation factor 1-alpha 1. (1|462)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • yes
  • none
  • unknown
  • likely

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?