P11835: Integrin beta-2 (Mouse)

Protein names
  • Integrin beta-2
  • Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta
  • Complement receptor C3 subunit beta
  • ITB2
Gene names Itgb2
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome (Not Available)

Sequence

        10         20         30         40         50         60 
MLGLRPSLLL ALAGLFFLGS AVSQECTKYK VSSCRDCIQS GPGCSWCQKL NFTGPGEPDS 
        70         80         90        100        110        120 
LRCDTRAQLL LKGCPADDIM DPRSIANPEF DQRGQRKQLS PQKVTLYLRP GQAAAFNVTF 
       130        140        150        160        170        180 
RRAKGYPIDL YYLMDLSYSM LDDLNNVKKL GGDLLQALNE ITESGRIGFG SFVDKTVLPF 
       190        200        210        220        230        240 
VNTHPEKLRN PCPNKEKACQ PPFAFRHVLK LTDNSNQFQT EVGKQLISGN LDAPEGGLDA 
       250        260        270        280        290        300 
IMQVAACPEE IGWRNVTRLL VFATDDGFHF AGDGKLGAIL TPNDGRCHLE DNMYKRSNEF 
       310        320        330        340        350        360 
DYPSVGQLAH KLSESNIQPI FAVTKKMVKT YEKLTEIIPK SAVGELSDDS SNVVQLIKNA 
       370        380        390        400        410        420 
YYKLSSRVFL DHSTLPDTLK VTYDSFCSNG ASSIGKSRGD CDGVQINNPV TFQVKVMASE 
       430        440        450        460        470        480 
CIQEQSFVIR ALGFTDTVTV QVRPQCECQC RDQSREQSLC GGKGVMECGI CRCESGYIGK 
       490        500        510        520        530        540 
NCECQTQGRS SQELERNCRK DNSSIVCSGL GDCICGQCVC HTSDVPNKEI FGQYCECDNV 
       550        560        570        580        590        600 
NCERYNSQVC GGSDRGSCNC GKCSCKPGYE GSACQCQRST TGCLNARLVE CSGRGHCQCN 
       610        620        630        640        650        660 
RCICDEGYQP PMCEDCPSCG SHCRDNHTSC AECLKFDKGP FEKNCSVQCA GMTLQTIPLK 
       670        680        690        700        710        720 
KKPCKERDSE GCWITYTLQQ KDGRNIYNIH VEDSLECVKG PNVAAIVGGT VVGVVLIGVL 
       730        740        750        760        770    
LLVIWKALTH LTDLREYRRF EKEKLKSQWN NDNPLFKSAT TTVMNPKFAE S

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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700
Chains:
 
 
N-termini:
NN
 
C-termini:
CC
 
Cleavage sites:
 
 
Features:
   
 
Binding & active sites:
    
 
Sequence variations:
   
 
Topology:
 
      
 
Modifications:
     
 
(PNVAA(705)|(706)IVGGT)
705,771

Matrix metalloproteinase-9 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Heinecke JW Vaisar T et al.:MMP-9 sheds the beta2 integrin ... (M10.004) unknown none

Targeted features: ?

705,771,771,24 CHAIN - Integrin beta-2. (24|771)
 
unknown-24QECTKY...
24,771

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

24,771,24,24 MOD_RES - Pyrrolidone carboxylic acid (By similarity). (24|24)
24,771,771,24 CHAIN - Integrin beta-2. (24|771)
24,771,702,24 TOPO_DOM - Extracellular (Potential). (24|702)
 
unknown-706IVGGTV...
706,771

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34621 indirect unknown (unknown)
 

Protein C-Termini [export]

...PNVAA705-unknown
705,771

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34621 indirect unknown (unknown)
 
...KFAES771-unknown
771,771

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

771,771,771,24 CHAIN - Integrin beta-2. (24|771)
771,771,771,726 TOPO_DOM - Cytoplasmic (Potential). (726|771)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • none
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?