P21589: 5'-nucleotidase (Human)

Protein names
  • 5'-nucleotidase (5'-NT)
  • Ecto-5'-nucleotidase (5'-NT)
  • 5NTD
Gene names NT5E
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 6

Isoforms

  • Isoform 2 of 5'-nucleotidase (P21589-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MCPRAARAPA TLLLALGAVL WPAAGAWELT ILHTNDVHSR LEQTSEDSSK CVNASRCMGG 
        70         80         90        100        110        120 
VARLFTKVQQ IRRAEPNVLL LDAGDQYQGT IWFTVYKGAE VAHFMNALRY DAMALGNHEF 
       130        140        150        160        170        180 
DNGVEGLIEP LLKEAKFPIL SANIKAKGPL ASQISGLYLP YKVLPVGDEV VGIVGYTSKE 
       190        200        210        220        230        240 
TPFLSNPGTN LVFEDEITAL QPEVDKLKTL NVNKIIALGH SGFEMDKLIA QKVRGVDVVV 
       250        260        270        280        290        300 
GGHSNTFLYT GNPPSKEVPA GKYPFIVTSD DGRKVPVVQA YAFGKYLGYL KIEFDERGNV 
       310        320        330        340        350        360 
ISSHGNPILL NSSIPEDPSI KADINKWRIK LDNYSTQELG KTIVYLDGSS QSCRFRECNM 
       370        380        390        400        410        420 
GNLICDAMIN NNLRHTDEMF WNHVSMCILN GGGIRSPIDE RNNGTITWEN LAAVLPFGGT 
       430        440        450        460        470        480 
FDLVQLKGST LKKAFEHSVH RYGQSTGEFL QVGGIHVVYD LSRKPGDRVV KLDVLCTKCR 
       490        500        510        520        530        540 
VPSYDPLKMD EVYKVILPNF LANGGDGFQM IKDELLRHDS GDQDINVVST YISKMKVIYP 
       550        560        570    
AVEGRIKFST GSHCHGSFSL IFLSLWAVIF VLYQ

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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400
500
Chains:
 
 
N-termini:

NNN
 
C-termini:
CC
 
Cleavage sites:
 
 
Features:
     
 
Binding & active sites:
   
         
 
Sequence variations:
    
 
Modifications:
 
 
(RIKFS(549)|(550)TGSHC)
549,574

GPI-anchor transamidase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Ikehara Y Misumi Y et al.:Primary structure of human plac... (C13.005) unknown yes

Affected feature boundaries: ?

549,574,549,549 LIPID - GPI-anchor amidated serine. (549|549)
549,574,548,544 STRAND - (544|548)
549,574,549,549 LIPID - GPI-anchor amidated serine. (549|549)
549,574,549,27 CHAIN - 5'-nucleotidase. (27|549)
549,574,574,550 PROPEP - Removed in mature form. (550|574)
 
unknown-1MCPRAA...
1,574

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt65830 indirect unknown (unknown)

Affected feature boundaries: ?

1,574,26,1 SIGNAL - (1|26)
 
unknown-27WELTIL...
27,574

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt114239 indirect unknown (unknown)

Affected feature boundaries: ?

27,574,34,27 STRAND - (27|34)
27,574,549,27 CHAIN - 5'-nucleotidase. (27|549)
 
unknown-550TGSHCH...
550,574

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC9869 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt153411 indirect unknown (unknown)

Affected feature boundaries: ?

550,574,574,550 PROPEP - Removed in mature form. (550|574)
 

Protein C-Termini [export]

...RIKFS549-unknown
549,574

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC9869 indirect unknown (unknown)

Affected feature boundaries: ?

549,574,549,549 LIPID - GPI-anchor amidated serine. (549|549)
549,574,549,27 CHAIN - 5'-nucleotidase. (27|549)
 
...FVLYQ574-unknown
574,574

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TCt61448 indirect unknown (unknown)

Affected feature boundaries: ?

574,574,574,550 PROPEP - Removed in mature form. (550|574)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?