P24394: Interleukin-4 receptor subunit alpha (Human)

Protein names
  • Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha)
  • IL4RA
Gene names IL4R
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 16

Isoforms

  • Isoform 2 of Interleukin-4 receptor subunit alpha (P24394-2): sequence view | extended view
  • Isoform 3 of Interleukin-4 receptor subunit alpha (P24394-3): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MGWLCSGLLF PVSCLVLLQV ASSGNMKVLQ EPTCVSDYMS ISTCEWKMNG PTNCSTELRL 
        70         80         90        100        110        120 
LYQLVFLLSE AHTCIPENNG GAGCVCHLLM DDVVSADNYT LDLWAGQQLL WKGSFKPSEH 
       130        140        150        160        170        180 
VKPRAPGNLT VHTNVSDTLL LTWSNPYPPD NYLYNHLTYA VNIWSENDPA DFRIYNVTYL 
       190        200        210        220        230        240 
EPSLRIAAST LKSGISYRAR VRAWAQCYNT TWSEWSPSTK WHNSYREPFE QHLLLGVSVS 
       250        260        270        280        290        300 
CIVILAVCLL CYVSITKIKK EWWDQIPNPA RSRLVAIIIQ DAQGSQWEKR SRGQEPAKCP 
       310        320        330        340        350        360 
HWKNCLTKLL PCFLEHNMKR DEDPHKAAKE MPFQGSGKSA WCPVEISKTV LWPESISVVR 
       370        380        390        400        410        420 
CVELFEAPVE CEEEEEVEEE KGSFCASPES SRDDFQEGRE GIVARLTESL FLDLLGEENG 
       430        440        450        460        470        480 
GFCQQDMGES CLLPPSGSTS AHMPWDEFPS AGPKEAPPWG KEQPLHLEPS PPASPTQSPD 
       490        500        510        520        530        540 
NLTCTETPLV IAGNPAYRSF SNSLSQSPCP RELGPDPLLA RHLEEVEPEM PCVPQLSEPT 
       550        560        570        580        590        600 
TVPQPEPETW EQILRRNVLQ HGAAAAPVSA PTSGYQEFVH AVEQGGTQAS AVVGLGPPGE 
       610        620        630        640        650        660 
AGYKAFSSLL ASSAVSPEKC GFGASSGEEG YKPFQDLIPG CPGDPAPVPV PLFTFGLDRE 
       670        680        690        700        710        720 
PPRSPQSSHL PSSSPEHLGL EPGEKVEDMP KPPLPQEQAT DPLVDSLGSG IVYSALTCHL 
       730        740        750        760        770        780 
CGHLKQCHGQ EDGGQTPVMA SPCCGCCCGD RSSPPTTPLR APDPSPGGVP LEASLCPASL 
       790        800        810        820    
APSGISEKSK SSSSFHPAPG NAQSSSQTPK IVNFVSVGPT YMRVS

Annotation ?

Network neighborhood
[show protein-protein interactions]
unknown-1MGWLCS...
1,825

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt77791 indirect unknown (unknown)

Affected feature boundaries: ?

1,825,23,1 VAR_SEQ - MGWLCSGLLFPVSCLVLLQVASS -> MQKDARRE (in isoform 3). (1|23)
1,825,25,1 SIGNAL - By similarity. (1|25)
 
unknown-26MKVLQE...
26,825

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from similarity UniProtKB inferred from uniprot (by similarity) unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt114006 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt114007 indirect unknown (unknown)

Affected feature boundaries: ?

26,825,232,26 TOPO_DOM - Extracellular (Potential). (26|232)
26,825,825,26 CHAIN - Interleukin-4 receptor subunit alpha. (26|825)
26,825,0,26 CHAIN - Soluble interleukin-4 receptor subunit alpha. (26|0)
 
unknown-179YLEPSL...
179,825

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt159809 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt159810 indirect unknown (unknown)
 

Protein C-Termini [export]

...YMRVS0-unknown
0,825

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,825,0,26 CHAIN - Soluble interleukin-4 receptor subunit alpha. (26|0)
 
...YMRVS825-unknown
825,825

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt73410 indirect unknown (unknown)

Affected feature boundaries: ?

825,825,825,228 VAR_SEQ - Missing (in isoform 2). (228|825)
825,825,825,257 TOPO_DOM - Cytoplasmic (Potential). (257|825)
825,825,825,26 CHAIN - Interleukin-4 receptor subunit alpha. (26|825)
 
Filter by evidence: ?

Directness ?

  • indirect
  • unknown

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?