P26439: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (Human)

Protein names
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2
  • 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II Short=3-beta-HSD II
  • 3-beta-HSD adrenal and gonadal type Includes: RecName: Full=3-beta-hydroxy-Delta(5)-steroid dehydrogenase EC=1.1.1.145
  • 3-beta-hydroxy-5-ene steroid dehydrogenase
  • Progesterone reductase Includes: RecName: Full=Steroid Delta-isomerase EC=5.3.3.1
  • Delta-5-3-ketosteroid isomerase
  • 3BHS2
Gene names HSD3B2 (HSDB3B)
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 1

Isoforms

  • Isoform 2 of 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (P26439-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MGWSCLVTGA GGLLGQRIVR LLVEEKELKE IRALDKAFRP ELREEFSKLQ NRTKLTVLEG 
        70         80         90        100        110        120 
DILDEPFLKR ACQDVSVVIH TACIIDVFGV THRESIMNVN VKGTQLLLEA CVQASVPVFI 
       130        140        150        160        170        180 
YTSSIEVAGP NSYKEIIQNG HEEEPLENTW PTPYPYSKKL AEKAVLAANG WNLKNGDTLY 
       190        200        210        220        230        240 
TCALRPTYIY GEGGPFLSAS INEALNNNGI LSSVGKFSTV NPVYVGNVAW AHILALRALR 
       250        260        270        280        290        300 
DPKKAPSVRG QFYYISDDTP HQSYDNLNYI LSKEFGLRLD SRWSLPLTLM YWIGFLLEVV 
       310        320        330        340        350        360 
SFLLSPIYSY QPPFNRHTVT LSNSVFTFSY KKAQRDLAYK PLYSWEEAKQ KTVEWVGSLV 
       370    
DRHKETLKSK TQ

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
Chains:
 
 
N-termini:

N
 
C-termini:
C
 
Binding & active sites:
  
 
Topology:
 
 
unknown-1MGWSCL...
1,372

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt65761 indirect unknown (unknown)

Affected feature boundaries: ?

1,372,372,1 CHAIN - 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2. (1|372)
 

Protein C-Termini [export]

...KSKTQ372-unknown
372,372

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

372,372,372,223 VAR_SEQ - Missing (in isoform 2). (223|372)
372,372,372,1 CHAIN - 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2. (1|372)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?