P33435: Collagenase 3 (Mouse)

Protein names
  • Collagenase 3
  • Matrix metalloproteinase-13 Short=MMP-13
  • MMP13
Gene names Mmp13
Organism Mus musculus
Protease Family M10 (MEROPS)
Protease ID M10.013 (MEROPS)
Chromosome 9

Sequence

        10         20         30         40         50         60 
MHSAILATFF LLSWTPCWSL PLPYGDDDDD DLSEEDLVFA EHYLKSYYHP ATLAGILKKS 
        70         80         90        100        110        120 
TVTSTVDRLR EMQSFFGLEV TGKLDDPTLD IMRKPRCGVP DVGEYNVFPR TLKWSQTNLT 
       130        140        150        160        170        180 
YRIVNYTPDM SHSEVEKAFR KAFKVWSDVT PLNFTRIYDG TADIMISFGT KEHGDFYPFD 
       190        200        210        220        230        240 
GPSGLLAHAF PPGPNYGGDA HFDDDETWTS SSKGYNLFIV AAHELGHSLG LDHSKDPGAL 
       250        260        270        280        290        300 
MFPIYTYTGK SHFMLPDDDV QGIQFLYGPG DEDPNPKHPK TPEKCDPALS LDAITSLRGE 
       310        320        330        340        350        360 
TMIFKDRFFW RLHPQQVEAE LFLTKSFWPE LPNHVDAAYE HPSRDLMFIF RGRKFWALNG 
       370        380        390        400        410        420 
YDILEGYPRK ISDLGFPKEV KRLSAAVHFE NTGKTLFFSE NHVWSYDDVN QTMDKDYPRL 
       430        440        450        460        470    
IEEEFPGIGN KVDAVYEKNG YIYFFNGPIQ FEYSIWSNRI VRVMPTNSIL WC

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
N-termini:
NN
 
C-termini:
C
 
Features:
  
   
 
unknown-20LPLPYG...
20,472

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

20,472,104,20 PROPEP - Activation peptide. (20|104)
 
unknown-105YNVFPR...
105,472

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

105,472,472,105 CHAIN - Collagenase 3. (105|472)
 

Protein C-Termini [export]

...SILWC472-unknown
472,472

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

472,472,472,429 REPEAT - Hemopexin 4. (429|472)
472,472,472,105 CHAIN - Collagenase 3. (105|472)
472,472,472,285 DISULFID - By similarity. (285|472)
472,472,472,269 REGION - Interaction with collagen (By similarity). (269|472)
 
44 (APSS.|.VIAA)
44,132

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Tester AM et al.:LPS responsiveness and neutroph... (M10.013) unknown yes
 
163 (KSAG.|.VSVP)
163,1453

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Jaenisch R Liu X et al.:A targeted mutation at the know... (M10.013) unknown yes
 
163 ()
163,1225

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC32749 indirect unknown
 
606 (DHAA.|.LTSC)
606,1191

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Maisi P Pirila E et al.:Matrix metalloproteinases proce... (M10.009) unknown yes
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?