P35213: 14-3-3 protein beta/alpha (Rat)

Protein names
  • 14-3-3 protein beta/alpha
  • 1433B
  • Prepronerve growth factor RNH-1
Gene names Ywhab
Organism Rattus norvegicus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 3

Isoforms

  • Isoform Short of 14-3-3 protein beta/alpha (P35213-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS 
        70         80         90        100        110        120 
WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICSDVL ELLDKYLILN ATHAESKVFY 
       130        140        150        160        170        180 
LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY 
       190        200        210        220        230        240 
YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD 
   
AGEGEN

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
Chains:
 
 
 
N-termini:

N
N
NNN
 
C-termini:
C
 
Features:
   
 
Sequence variations:
 
 
Modifications:
           
 
acetylation-1MTMDKS...
1,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
1,246,1,1 MOD_RES - N-acetylmethionine. {ECO:0000250|UniProtKB:P31946}. (1|1)
1,246,1,1 INIT_MET - Removed; alternate. {ECO:0000250|UniProtKB:P31946, ECO:0000250|UniProtKB:P68250}. (1|1)
1,246,2,1 VAR_SEQ - Missing (in isoform Short). {ECO:0000305}. (1|2)
 
acetylation-2TMDKSE...
2,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Doskeland, PROBE RAT-leukemia-IPC81-Bortezomib-AD direct yes 0.05 (MASCOT score)

Affected feature boundaries: ?

2,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
2,246,2,2 MOD_RES - N-acetylthreonine; in 14-3-3 protein beta/alpha, N-terminally processed. {ECO:0000250|UniProtKB:P31946}. (2|2)
 
unknown-3MDKSEL...
3,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt192181 indirect unknown (unknown)
 
unknown-51KNVVGA...
51,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Doskeland, PROBE RAT-leukemia-IPC81-Bortezomib-AD direct yes 0.05 (MASCOT score)
Doskeland, PROBE RAT-leukemia-IPC81-IDA+Btz-AD direct yes 0.05 (MASCOT score)

Affected feature boundaries: ?

51,246,51,51 MOD_RES - N6-acetyllysine. {ECO:0000250|UniProtKB:P27348}. (51|51)
 
unknown-120YLKMKG...
120,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Doskeland, PROBE RAT-leukemia-IPC81-Bortezomib-AD direct yes 0.05 (MASCOT score)
 

Protein C-Termini [export]

...GEGEN246-unknown
246,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

246,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
246,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct
  • indirect

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • MASCOT score

Experimental system ?

Certainty of Protease assignment ?

  • unknown
  • IV proteolytic system present and active

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?