P38182: Autophagy-related protein 8 (strain ATCC 204508 / S288c) (Baker's yeast)

Protein names
  • Autophagy-related protein 8
  • Autophagy-related ubiquitin-like modifier ATG8
  • Cytoplasm to vacuole targeting protein 5
  • ATG8
Gene names ATG8 (APG8, AUT7, CVT5)
Organism Saccharomyces cerevisiae
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome II

Sequence

        10         20         30         40         50         60 
MKSTFKSEYP FEKRKAESER IADRFKNRIP VICEKAEKSD IPEIDKRKYL VPADLTVGQF 
        70         80         90        100        110    
VYVIRKRIML PPEKAIFIFV NDTLPPTAAL MSAIYQEHKD KDGFLYVTYS GENTFGR

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
Chains:
 
 
N-termini:

N
 
C-termini:
C
 
Cleavage sites:
 
 
Features:
 
 
 
Sequence variations:
            
 
Modifications:
 
 
(ENTFG(116)|(117)R)
116,117

Cysteine protease ATG4 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops ATG4_YEAST -> ATG8_YEAST @116 unknown yes

Affected feature boundaries: ?

116,117,117,116 SITE - Cleavage; by ATG4. (116|117)
116,117,116,116 MUTAGEN - G->A: No cleaving of the C-terminal R-117 by ATG4. Defect in Cvt pathway and autophagy. (116|116)
116,117,116,116 LIPID - Phosphatidylethanolamine amidated glycine. (116|116)
116,117,116,116 MUTAGEN - G->A: No cleaving of the C-terminal R-117 by ATG4. Defect in Cvt pathway and autophagy. (116|116)
116,117,117,117 MUTAGEN - R->M: Normal processing after G-116 by ATG4. (117|117)
116,117,116,1 CHAIN - Autophagy-related protein 8. (1|116)
116,117,117,117 PROPEP - Removed in mature form. (117|117)
116,117,116,116 LIPID - Phosphatidylethanolamine amidated glycine. (116|116)
 
unknown-1MKSTFK...
1,117

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,117,116,1 CHAIN - Autophagy-related protein 8. (1|116)
 

Protein C-Termini [export]

...ENTFG116-unknown
116,117

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC27863 indirect unknown (unknown)

Affected feature boundaries: ?

116,117,116,116 MUTAGEN - G->A: No cleaving of the C-terminal R-117 by ATG4. Defect in Cvt pathway and autophagy. (116|116)
116,117,116,1 CHAIN - Autophagy-related protein 8. (1|116)
116,117,116,116 LIPID - Phosphatidylethanolamine amidated glycine. (116|116)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?