P42208: Neural precursor cell expressed developmentally down-regulated protein 5 Short=NEDD-5 (Mouse)

Protein names
  • Neural precursor cell expressed developmentally down-regulated protein 5 Short=NEDD-5
Gene names Sept2 (Nedd-5, Nedd5)
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 1

Sequence

        10         20         30         40         50         60 
MSKQQPTQFI NPETPGYVGF ANLPNQVHRK SVKKGFEFTL MVVGESGLGK STLINSLFLT 
        70         80         90        100        110        120 
DLYPERIIPG AAEKIERTVQ IEASTVEIEE RGVKLRLTVV DTPGYGDAIN CRDCFKTIIS 
       130        140        150        160        170        180 
YIDEQFERYL HDESGLNRRH IIDNRVHCCF YFISPFGHGL KPLDVAFMKA IHNKVNIVPV 
       190        200        210        220        230        240 
IAKADTLTLK ERERLKKRIL DEIEEHSIKI YHLPDAESDE DEDFKEQTRL LKASIPFSVV 
       250        260        270        280        290        300 
GSNQLIEAKG KKVRGRLYPW GVVEVENPEH NDFLKLRTML ITHMQDLQEV TQDLHYENFR 
       310        320        330        340        350        360 
SERLKRGGRK VENEDMNKDQ ILLEKEAELR RMQEMIARMQ AQMQMQMQGG DSDSGALGQH 
   
V

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
Chains:
 
 
N-termini:

N
NNNNNNN
N
 
C-termini:
CCCCCC
CCCCCC
 
Cleavage sites:
    
  
 
Features:
  
 
Binding & active sites:
       
 
Sequence variations:
     
 
Modifications:
   
 
(QQPTQ(8)|(9)FINPE)
8,361

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

8,361,361,1 CHAIN - Septin-2. (1|361)
 
(VNIVP(179)|(180)VIAKA)
179,361

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

179,361,361,1 CHAIN - Septin-2. (1|361)
 
(SIPFS(238)|(239)VVGSN)
238,361

Matrix metalloproteinase-9 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

Targeted features: ?

238,361,361,1 CHAIN - Septin-2. (1|361)

Affected feature boundaries: ?

238,361,238,236 STRAND - (236|238)
 
(GSNQL(245)|(246)IEAKG)
245,361

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> SEPT2_MOUSE @245 unknown yes

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> SEPT2_MOUSE @245 unknown yes

Targeted features: ?

245,361,361,1 CHAIN - Septin-2. (1|361)

Affected feature boundaries: ?

245,361,247,245 STRAND - (245|247)
 
(LYPWG(261)|(262)VVEVE)
261,361

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

261,361,361,1 CHAIN - Septin-2. (1|361)

Affected feature boundaries: ?

261,361,264,261 STRAND - (261|264)
 
unknown-1MSKQQP...
1,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,361,361,1 CHAIN - Septin-2. (1|361)
 
acetylation-2SKQQPT...
2,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall CM. Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... direct likely 0.0 (unknown)
Overall CM. Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... direct likely 0.0 (unknown)
 
unknown-9FINPET...
9,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33554 indirect unknown (unknown)
 
unknown-41MVVGES...
41,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000118621 unknown unknown (unknown)
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000127276 unknown unknown (unknown)
 
unknown-180VIAKAD...
180,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33555 indirect unknown (unknown)
 
unknown-239VVGSNQ...
239,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34625 indirect unknown (unknown)
 
unknown-246IEAKGK...
246,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28876 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29943 indirect unknown (unknown)
 
unknown-262VVEVEN...
262,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33556 indirect unknown (unknown)
 
unknown-266ENPEHN...
266,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall CM. Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... direct likely 0.0 (unknown)
 

Protein C-Termini [export]

...QQPTQ8-unknown
8,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33554 indirect unknown (unknown)
 
...EKIER77-unknown
77,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000114614 unknown unknown (unknown)
 
...KTIIS120-unknown
120,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000115536 unknown unknown (unknown)
 
...DNRVH147-unknown
147,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000118621 unknown unknown (unknown)
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000121974 unknown unknown (unknown)
 
...VNIVP179-unknown
179,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33555 indirect unknown (unknown)
 
...IKIYH212-unknown
212,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000120694 unknown unknown (unknown)
 
...KIYHL213-unknown
213,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000120511 unknown unknown (unknown)
 
...ESDED221-unknown
221,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000108534 unknown unknown (unknown)
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000117517 unknown unknown (unknown)
 
...SIPFS238-unknown
238,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34625 indirect unknown (unknown)

Affected feature boundaries: ?

238,361,238,236 STRAND - (236|238)
 
...GSNQL245-unknown
245,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC28876 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29943 indirect unknown (unknown)
 
...LYPWG261-unknown
261,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33556 indirect unknown (unknown)
 
...LGQHV361-unknown
361,361

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

361,361,361,1 CHAIN - Septin-2. (1|361)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct
  • indirect

Physiological relevance ?

  • none
  • yes
  • unknown
  • likely

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?