P51793: H(+)/Cl(-) exchange transporter 4 (Human)

Protein names
  • H(+)/Cl(-) exchange transporter 4
  • Chloride channel protein 4 Short=ClC-4
  • Chloride transporter ClC-4
  • CLCN4
Gene names CLCN4
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome X

Isoforms

  • Isoform 2 of H(+)/Cl(-) exchange transporter 4 (P51793-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MVNAGAMSGS GNLMDFLDEP FPDVGTYEDF HTIDWLREKS RDTDRHRKIT SKSKESIWEF 
        70         80         90        100        110        120 
IKSLLDAWSG WVVMLLIGLL AGTLAGVIDL AVDWMTDLKE GVCLSAFWYS HEQCCWTSNE 
       130        140        150        160        170        180 
TTFEDRDKCP LWQKWSELLV NQSEGASAYI LNYLMYILWA LLFAFLAVSL VRVFAPYACG 
       190        200        210        220        230        240 
SGIPEIKTIL SGFIIRGYLG KWTLLIKTVT LVLVVSSGLS LGKEGPLVHV ACCCGNFFSS 
       250        260        270        280        290        300 
LFSKYSKNEG KRREVLSAAA AAGVSVAFGA PIGGVLFSLE EVSYYFPLKT LWRSFFAALV 
       310        320        330        340        350        360 
AAFTLRSINP FGNSRLVLFY VEYHTPWYMA ELFPFILLGV FGGLWGTLFI RCNIAWCRRR 
       370        380        390        400        410        420 
KTTRLGKYPV LEVIVVTAIT AIIAYPNPYT RQSTSELISE LFNDCGALES SQLCDYINDP 
       430        440        450        460        470        480 
NMTRPVDDIP DRPAGVGVYT AMWQLALALI FKIVVTIFTF GMKIPSGLFI PSMAVGAIAG 
       490        500        510        520        530        540 
RMVGIGVEQL AYHHHDWIIF RNWCRPGADC VTPGLYAMVG AAACLGGVTR MTVSLVVIMF 
       550        560        570        580        590        600 
ELTGGLEYIV PLMAAAVTSK WVADAFGKEG IYEAHIHLNG YPFLDVKDEF THRTLATDVM 
       610        620        630        640        650        660 
RPRRGEPPLS VLTQDSMTVE DVETLIKETD YNGFPVVVSR DSERLIGFAQ RRELILAIKN 
       670        680        690        700        710        720 
ARQRQEGIVS NSIMYFTEEP PELPANSPHP LKLRRILNLS PFTVTDHTPM ETVVDIFRKL 
       730        740        750        760    
GLRQCLVTRS GRLLGIITKK DVLRHMAQMA NQDPESIMFN 

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
N-termini:

NN
 
C-termini:
C
 
Features:
  
     
 
Binding & active sites:
      
 
Sequence variations:
      
 
unknown-1MVNAGA...
1,760

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,760,94,1 VAR_SEQ - Missing (in isoform 2). (1|94)
1,760,67,1 TOPO_DOM - Cytoplasmic (By similarity). (1|67)
1,760,760,1 CHAIN - H(+)/Cl(-) exchange transporter 4. (1|760)
 
unknown-95MTDLKE...
95,760

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt70928 indirect unknown (unknown)
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000405754 unknown unknown (unknown)
 

Protein C-Termini [export]

...SIMFN760-unknown
760,760

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt66546 indirect unknown (unknown)

Affected feature boundaries: ?

760,760,760,567 TOPO_DOM - Cytoplasmic (By similarity). (567|760)
760,760,760,1 CHAIN - H(+)/Cl(-) exchange transporter 4. (1|760)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?