P68254: 14-3-3 protein theta (Mouse)

Protein names
  • 14-3-3 protein theta
  • 14-3-3 protein tau
  • 1433T
Gene names Ywhaq
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 12

Isoforms

  • Isoform 2 of 14-3-3 protein theta (P68254-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MEKTELIQKA KLAEQAERYD DMATCMKAVT EQGAELSNEE RNLLSVAYKN VVGGRRSAWR 
        70         80         90        100        110        120 
VISSIEQKTD TSDKKLQLIK DYREKVESEL RSICTTVLEL LDKYLIANAT NPESKVFYLK 
       130        140        150        160        170        180 
MKGDYFRYLA EVACGDDRKQ TIENSQGAYQ EAFDISKKEM QPTHPIRLGL ALNFSVFYYE 
       190        200        210        220        230        240 
ILNNPELACT LAKTAFDEAI AELDTLNEDS YKDSTLIMQL LRDNLTLWTS DSAGEECDAA 
   
EGAEN

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
Chains:
 
 
N-termini:

N
NNN
N
NN
 
C-termini:
CC
C
CCC
 
Cleavage sites:
 
   
   
 
Features:
  
 
Sequence variations:
  
 
 
Modifications:
      
 
(EKTEL(6)|(7)IQKAK)
6,245

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433T_MOUSE @6 unknown yes

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Zornig M Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009) unknown yes

Targeted features: ?

6,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
 
(DMATC(25)|(26)MKAVT)
25,245

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops MMP2_MOUSE -> 1433T_MOUSE @25 unknown none

Targeted features: ?

25,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)

Affected feature boundaries: ?

25,245,26,26 CONFLICT - M -> I (in Ref. 4; BAE35397). (26|26)
 
(MATCM(26)|(27)KAVTE)
26,245

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433T_MOUSE @26 unknown yes

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATD_MOUSE -> 1433T_MOUSE @26 unknown yes

Targeted features: ?

26,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)

Affected feature boundaries: ?

26,245,26,26 CONFLICT - M -> I (in Ref. 4; BAE35397). (26|26)
26,245,26,26 CONFLICT - M -> I (in Ref. 4; BAE35397). (26|26)
 
(TCMKA(28)|(29)VTEQG)
28,245

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433T_MOUSE @28 unknown yes

Targeted features: ?

28,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
 
(ERNLL(44)|(45)SVAYK)
44,245

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433T_MOUSE @44 unknown yes

Targeted features: ?

44,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
 
unknown-1MEKTEL...
1,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt65722 indirect unknown (unknown)

Affected feature boundaries: ?

1,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
1,245,1,1 MOD_RES - N-acetylmethionine (By similarity). (1|1)
 
acetylation-1MEKTEL...
1,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Overall CM. Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... direct likely 0.0 (unknown)
Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from... unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt108013 indirect unknown (unknown)

Affected feature boundaries: ?

1,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
1,245,1,1 MOD_RES - N-acetylmethionine (By similarity). (1|1)
 
unknown-7IQKAKL...
7,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30299 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29060 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt194765 indirect unknown (unknown)
 
unknown-26MKAVTE...
26,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33773 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt137304 indirect unknown (unknown)

Affected feature boundaries: ?

26,245,26,26 CONFLICT - M -> I (in Ref. 4; BAE35397). (26|26)
 
unknown-27KAVTEQ...
27,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30300 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29061 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt137339 indirect unknown (unknown)
 
unknown-29VTEQGA...
29,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30302 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt137463 indirect unknown (unknown)
 
unknown-45SVAYKN...
45,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30304 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt138740 indirect unknown (unknown)
 

Protein C-Termini [export]

...EKTEL6-unknown
6,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30299 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29060 indirect unknown (unknown)
 
...DMATC25-unknown
25,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC33773 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt120238 indirect unknown (unknown)
 
...MATCM26-unknown
26,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30300 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29061 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt120283 indirect unknown (unknown)

Affected feature boundaries: ?

26,245,26,26 CONFLICT - M -> I (in Ref. 4; BAE35397). (26|26)
 
...TCMKA28-unknown
28,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30302 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt120429 indirect unknown (unknown)
 
...ERNLL44-unknown
44,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC30304 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt121794 indirect unknown (unknown)
 
...EGAEN245-unknown
245,245

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

245,245,245,227 VAR_SEQ - LWTSDSAGEECDAAEGAEN -> FTCVELETVSVCFSLLS (in isoform 2). (227|245)
245,245,245,1 CHAIN - 14-3-3 protein theta. (1|245)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • yes
  • none
  • unknown
  • likely

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?