Q13018: Secretory phospholipase A2 receptor (Human)

Protein names
  • Secretory phospholipase A2 receptor (PLA2-R)
  • 180 kDa secretory phospholipase A2 receptor (PLA2-R)
  • C-type lectin domain family 13 member C (PLA2-R)
  • M-type receptor (PLA2-R)
  • PLA2R
Gene names PLA2R1 (CLEC13C)
Organism Homo sapiens
Protease Family S63 (MEROPS)
Protease ID S63.015 (MEROPS)
Chromosome 2

Isoforms

  • Isoform 2 of Secretory phospholipase A2 receptor (Q13018-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MLLSPSLLLL LLLGAPRGCA EGVAAALTPE RLLEWQDKGI FVIQSESLKK CIQAGKSVLT 
        70         80         90        100        110        120 
LENCKQANKH MLWKWVSNHG LFNIGGSGCL GLNFSAPEQP LSLYECDSTL VSLRWRCNRK 
       130        140        150        160        170        180 
MITGPLQYSV QVAHDNTVVA SRKYIHKWIS YGSGGGDICE YLHKDLHTIK GNTHGMPCMF 
       190        200        210        220        230        240 
PFQYNHQWHH ECTREGREDD LLWCATTSRY ERDEKWGFCP DPTSAEVGCD TIWEKDLNSH 
       250        260        270        280        290        300 
ICYQFNLLSS LSWSEAHSSC QMQGGTLLSI TDETEENFIR EHMSSKTVEV WMGLNQLDEH 
       310        320        330        340        350        360 
AGWQWSDGTP LNYLNWSPEV NFEPFVEDHC GTFSSFMPSA WRSRDCESTL PYICKKYLNH 
       370        380        390        400        410        420 
IDHEIVEKDA WKYYATHCEP GWNPYNRNCY KLQKEEKTWH EALRSCQADN SALIDITSLA 
       430        440        450        460        470        480 
EVEFLVTLLG DENASETWIG LSSNKIPVSF EWSNDSSVIF TNWHTLEPHI FPNRSQLCVS 
       490        500        510        520        530        540 
AEQSEGHWKV KNCEERLFYI CKKAGHVLSD AESGCQEGWE RHGGFCYKID TVLRSFDQAS 
       550        560        570        580        590        600 
SGYYCPPALV TITNRFEQAF ITSLISSVVK MKDSYFWIAL QDQNDTGEYT WKPVGQKPEP 
       610        620        630        640        650        660 
VQYTHWNTHQ PRYSGGCVAM RGRHPLGRWE VKHCRHFKAM SLCKQPVENQ EKAEYEERWP 
       670        680        690        700        710        720 
FHPCYLDWES EPGLASCFKV FHSEKVLMKR TWREAEAFCE EFGAHLASFA HIEEENFVNE 
       730        740        750        760        770        780 
LLHSKFNWTE ERQFWIGFNK RNPLNAGSWE WSDRTPVVSS FLDNTYFGED ARNCAVYKAN 
       790        800        810        820        830        840 
KTLLPLHCGS KREWICKIPR DVKPKIPFWY QYDVPWLFYQ DAEYLFHTFA SEWLNFEFVC 
       850        860        870        880        890        900 
SWLHSDLLTI HSAHEQEFIH SKIKALSKYG ASWWIGLQEE RANDEFRWRD GTPVIYQNWD 
       910        920        930        940        950        960 
TGRERTVNNQ SQRCGFISSI TGLWGSEECS VSMPSICKRK KVWLIEKKKD TPKQHGTCPK 
       970        980        990       1000       1010       1020 
GWLYFNYKCL LLNIPKDPSS WKNWTHAQHF CAEEGGTLVA IESEVEQAFI TMNLFGQTTS 
      1030       1040       1050       1060       1070       1080 
VWIGLQNDDY ETWLNGKPVV YSNWSPFDII NIPSHNTTEV QKHIPLCALL SSNPNFHFTG 
      1090       1100       1110       1120       1130       1140 
KWYFEDCGKE GYGFVCEKMQ DTSGHGVNTS DMYPMPNTLE YGNRTYKIIN ANMTWYAAIK 
      1150       1160       1170       1180       1190       1200 
TCLMHKAQLV SITDQYHQSF LTVVLNRLGY AHWIGLFTTD NGLNFDWSDG TKSSFTFWKD 
      1210       1220       1230       1240       1250       1260 
EESSLLGDCV FADSNGRWHS TACESFLQGA ICHVPPETRQ SEHPELCSET SIPWIKFKSN 
      1270       1280       1290       1300       1310       1320 
CYSFSTVLDS MSFEAAHEFC KKEGSNLLTI KDEAENAFLL EELFAFGSSV QMVWLNAQFD 
      1330       1340       1350       1360       1370       1380 
GNNETIKWFD GTPTDQSNWG IRKPDTDYFK PHHCVALRIP EGLWQLSPCQ EKKGFICKME 
      1390       1400       1410       1420       1430       1440 
ADIHTAEALP EKGPSHSIIP LAVVLTLIVI VAICTLSFCI YKHNGGFFRR LAGFRNPYYP 
      1450       1460    
ATNFSTVYLE ENILISDLEK SDQ

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
 
N-termini:

NN
 
C-termini:

CC
 
Topology:
   
 
unknown-1MLLSPS...
1,1463

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt85463 indirect unknown (unknown)

Affected feature boundaries: ?

1,1463,20,1 SIGNAL - By similarity. (1|20)
 
unknown-21EGVAAA...
21,1463

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from similarity UniProtKB inferred from uniprot (by similarity) unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt112557 indirect unknown (unknown)

Affected feature boundaries: ?

21,1463,1463,21 CHAIN - Secretory phospholipase A2 receptor. (21|1463)
21,1463,0,21 CHAIN - Soluble secretory phospholipase A2 receptor (By similarity). (21|0)
21,1463,1397,21 TOPO_DOM - Extracellular (Potential). (21|1397)
 

Protein C-Termini [export]

...EKSDQ0-unknown
0,1463

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,1463,0,21 CHAIN - Soluble secretory phospholipase A2 receptor (By similarity). (21|0)
 
...EKSDQ1463-unknown
1463,1463

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1463,1463,1463,21 CHAIN - Secretory phospholipase A2 receptor. (21|1463)
1463,1463,1463,1419 TOPO_DOM - Cytoplasmic (Potential). (1419|1463)
1463,1463,1463,1325 VAR_SEQ - Missing (in isoform 2). (1325|1463)
 
Filter by evidence: ?

Directness ?

  • indirect
  • unknown

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?