Q14511: Enhancer of filamentation 1 (Human)

Protein names
  • Enhancer of filamentation 1 (hEF1)
  • CRK-associated substrate-related protein Short=CAS-L Short=CasL (hEF1)
  • Cas scaffolding protein family member 2 (hEF1)
  • Neural precursor cell expressed developmentally down-regulated protein 9 Short=NEDD-9 (hEF1)
  • Renal carcinoma antigen NY-REN-12 (hEF1)
  • p105 (hEF1)
  • CASL
Gene names NEDD9 (CASL, CASS2)
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 6

Isoforms

  • Isoform 2 of Enhancer of filamentation 1 (Q14511-2): sequence view | extended view
  • Isoform 3 of Enhancer of filamentation 1 (Q14511-3): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MKYKNLMARA LYDNVPECAE ELAFRKGDIL TVIEQNTGGL EGWWLCSLHG RQGIVPGNRV 
        70         80         90        100        110        120 
KLLIGPMQET ASSHEQPASG LMQQTFGQQK LYQVPNPQAA PRDTIYQVPP SYQNQGIYQV 
       130        140        150        160        170        180 
PTGHGTQEQE VYQVPPSVQR SIGGTSGPHV GKKVITPVRT GHGYVYEYPS RYQKDVYDIP 
       190        200        210        220        230        240 
PSHTTQGVYD IPPSSAKGPV FSVPVGEIKP QGVYDIPPTK GVYAIPPSAC RDEAGLREKD 
       250        260        270        280        290        300 
YDFPPPMRQA GRPDLRPEGV YDIPPTCTKP AGKDLHVKYN CDIPGAAEPV ARRHQSLSPN 
       310        320        330        340        350        360 
HPPPQLGQSV GSQNDAYDVP RGVQFLEPPA ETSEKANPQE RDGVYDVPLH NPPDAKGSRD 
       370        380        390        400        410        420 
LVDGINRLSF SSTGSTRSNM STSSTSSKES SLSASPAQDK RLFLDPDTAI ERLQRLQQAL 
       430        440        450        460        470        480 
EMGVSSLMAL VTTDWRCYGY MERHINEIRT AVDKVELFLK EYLHFVKGAV ANAACLPELI 
       490        500        510        520        530        540 
LHNKMKRELQ RVEDSHQILS QTSHDLNECS WSLNILAINK PQNKCDDLDR FVMVAKTVPD 
       550        560        570        580        590        600 
DAKQLTTTIN TNAEALFRPG PGSLHLKNGP ESIMNSTEYP HGGSQGQLLH PGDHKAQAHN 
       610        620        630        640        650        660 
KALPPGLSKE QAPDCSSSDG SERSWMDDYD YVHLQGKEEF ERQQKELLEK ENIMKQNKMQ 
       670        680        690        700        710        720 
LEHHQLSQFQ LLEQEITKPV ENDISKWKPS QSLPTTNSGV SAQDRQLLCF YYDQCETHFI 
       730        740        750        760        770        780 
SLLNAIDALF SCVSSAQPPR IFVAHSKFVI LSAHKLVFIG DTLTRQVTAQ DIRNKVMNSS 
       790        800        810        820        830    
NQLCEQLKTI VMATKMAALH YPSTTALQEM VHQVTDLSRN AQLFKRSLLE MATF

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
 
N-termini:

NN
N
 
C-termini:

CC
 
Features:
    
 
Sequence variations:
    
   
 
Modifications:
  
 
unknown-1MKYKNL...
1,834

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt69327 indirect unknown (unknown)
Gevaert K. Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)

Affected feature boundaries: ?

1,834,4,1 VAR_SEQ - MKYK -> MWTR (in isoform 3). (1|4)
1,834,834,1 CHAIN - Enhancer of filamentation 1. (1|834)
1,834,0,1 CHAIN - Enhancer of filamentation 1 p55. (1|0)
 
unknown-631YVHLQG...
631,834

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt178357 indirect unknown (unknown)
 
unknown-631YVHLQG...
631,834

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Wells apoptosis_U266_bortezomib_induced direct yes 0.02 (ProteinProspector)
 

Protein C-Termini [export]

...EMATF0-unknown
0,834

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,834,0,1 CHAIN - Enhancer of filamentation 1 p55. (1|0)
 
...EMATF834-unknown
834,834

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt64946 indirect unknown (unknown)

Affected feature boundaries: ?

834,834,834,175 VAR_SEQ - Missing (in isoform 2). (175|834)
834,834,834,1 CHAIN - Enhancer of filamentation 1. (1|834)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • ProteinProspector

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?