Q15173: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (Human)

Protein names
  • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
  • PP2A B subunit isoform B'-beta
  • PP2A B subunit isoform B56-beta
  • PP2A B subunit isoform PR61-beta
  • PP2A B subunit isoform R5-beta
  • 2A5B
Gene names PPP2R5B
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 11

Isoforms

  • Isoform Beta-2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform (Q15173-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
METKLPPAST PTSPSSPGLS PVPPPDKVDG FSRRSLRRAR PRRSHSSSQF RYQSNQQELT 
        70         80         90        100        110        120 
PLPLLKDVPA SELHELLSRK LAQCGVMFDF LDCVADLKGK EVKRAALNEL VECVGSTRGV 
       130        140        150        160        170        180 
LIEPVYPDII RMISVNIFRT LPPSENPEFD PEEDEPNLEP SWPHLQLVYE FFLRFLESPD 
       190        200        210        220        230        240 
FQPSVAKRYV DQKFVLMLLE LFDSEDPRER EYLKTILHRV YGKFLGLRAY IRKQCNHIFL 
       250        260        270        280        290        300 
RFIYEFEHFN GVAELLEILG SIINGFALPL KTEHKQFLVR VLIPLHSVKS LSVFHAQLAY 
       310        320        330        340        350        360 
CVVQFLEKDA TLTEHVIRGL LKYWPKTCTQ KEVMFLGEME EILDVIEPSQ FVKIQEPLFK 
       370        380        390        400        410        420 
QVARCVSSPH FQVAERALYF WNNEYILSLI EDNCHTVLPA VFGTLYQVSK EHWNQTIVSL 
       430        440        450        460        470        480 
IYNVLKTFME MNGKLFDELT ASYKLEKQQE QQKAQERQEL WQGLEELRLR RLQGTQGAKE 
       490    
APLQRLTPQV AASGGQS

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
N-termini:

N
N
 
C-termini:
C
C
 
Sequence variations:
      
 
Modifications:
      
 
acetylation-1METKLP...
1,497

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall Laboratory Lange_Huesgen_et_al-RBC direct yes 0.88 (PeptideProphet probability)

Affected feature boundaries: ?

1,497,19,1 VAR_SEQ - METKLPPASTPTSPSSPGL -> MITVNPPLPQDTVNLF (in isoform Beta-2). (1|19)
1,497,497,1 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. (1|497)
 
unknown-1METKLP...
1,497

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,497,19,1 VAR_SEQ - METKLPPASTPTSPSSPGL -> MITVNPPLPQDTVNLF (in isoform Beta-2). (1|19)
1,497,497,1 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. (1|497)
 

Protein C-Termini [export]

...SGGQS497-unknown
497,497

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt61348 indirect unknown (unknown)
Gevaert K. Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)

Affected feature boundaries: ?

497,497,497,1 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. (1|497)
 
...SGGQS497-unknown
497,497

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Gevaert K. Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)

Affected feature boundaries: ?

497,497,497,1 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform. (1|497)
 
Filter by evidence: ?

Directness ?

  • direct
  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • PeptideProphet probability
  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • IV proteolytic system present and active
  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?