Q16537: Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (Human)

Protein names
  • Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
  • PP2A B subunit isoform B'-epsilon
  • PP2A B subunit isoform B56-epsilon
  • PP2A B subunit isoform PR61-epsilon
  • PP2A B subunit isoform R5-epsilon
  • 2A5E
Gene names PPP2R5E
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 14

Isoforms

  • Isoform 2 of Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform (Q16537-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MSSAPTTPPS VDKVDGFSRK SVRKARQKRS QSSSQFRSQG KPIELTPLPL LKDVPSSEQP 
        70         80         90        100        110        120 
ELFLKKLQQC CVIFDFMDTL SDLKMKEYKR STLNELVDYI TISRGCLTEQ TYPEVVRMVS 
       130        140        150        160        170        180 
CNIFRTLPPS DSNEFDPEED EPTLEASWPH LQLVYEFFIR FLESQEFQPS IAKKYIDQKF 
       190        200        210        220        230        240 
VLQLLELFDS EDPRERDYLK TVLHRIYGKF LGLRAFIRKQ INNIFLRFVY ETEHFNGVAE 
       250        260        270        280        290        300 
LLEILGSIIN GFALPLKAEH KQFLVKVLIP LHTVRSLSLF HAQLAYCIVQ FLEKDPSLTE 
       310        320        330        340        350        360 
PVIRGLMKFW PKTCSQKEVM FLGELEEILD VIEPSQFVKI QEPLFKQIAK CVSSPHFQVA 
       370        380        390        400        410        420 
ERALYYWNNE YIMSLIEENS NVILPIMFSS LYRISKEHWN PAIVALVYNV LKAFMEMNST 
       430        440        450        460    
MFDELTATYK SDRQREKKKE KEREELWKKL EDLELKRGLR RDGIIPT

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
N-termini:

N
N
NN
 
C-termini:
C
 
Features:
 
 
Sequence variations:
 
 
Modifications:
    
 
unknown-1MSSAPT...
1,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,467,1,1 INIT_MET - Removed. (1|1)
 
unknown-1MSSAPT...
1,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt65733 indirect unknown (unknown)

Affected feature boundaries: ?

1,467,1,1 INIT_MET - Removed. (1|1)
 
acetylation-2SSAPTT...
2,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Gevaert K. Van Damme P et al.: Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)
Gevaert K. Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt110672 indirect unknown (unknown)

Affected feature boundaries: ?

2,467,2,2 MOD_RES - N-acetylserine. (2|2)
2,467,467,2 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform. (2|467)
 
unknown-77MDTLSD...
77,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000404632 unknown unknown (unknown)
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt131451 indirect unknown (unknown)
 

Protein C-Termini [export]

...GIIPT467-unknown
467,467

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt61351 indirect unknown (unknown)

Affected feature boundaries: ?

467,467,467,2 CHAIN - Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform. (2|467)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?