Q5XIE8: Integral membrane protein 2B (Rat)

Protein names
  • Integral membrane protein 2B
  • ITM2B
  • Immature BRI2
  • Transmembrane protein BRI
Gene names Itm2b
Organism Rattus norvegicus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 15

Sequence

        10         20         30         40         50         60 
MVKVTFNSAL AQKEAKKDEP KSSEEALIAP PDAVAVDCKD PDDVVPVGQR RAWCWCMCFG 
        70         80         90        100        110        120 
LAFMLAGVIL GGAYLYKYFA LQPDDVYYCG LKYIKDDVIL SEPSADAPAA RYQTIEENIK 
       130        140        150        160        170        180 
IFEEDAVEFI SVPVPEFADS DPANIVHDFN KKLTAYLDLN LDKCYVIPLN TSIVMPPRNL 
       190        200        210        220        230        240 
LELLINIKAG TYLPQSYLIH EHMVITDRIE NVDHLGFFIY RLCHDKETYK LQRRETIRGI 
       250        260    
QKREASNCFT IRHFENKFAV ETLICS

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
Chains:
 
 
 
 
 
N-termini:

N
NN
 
C-termini:

CCC
 
Features:
   
 
 
Topology:
   
 
unknown-0SMVKVT...
0,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,266,243,0 CHAIN - BRI2C, soluble form. {ECO:0000250}. (0|243)
 
unknown-1MVKVTF...
1,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,266,266,1 CHAIN - Integral membrane protein 2B. (1|266)
1,266,243,1 CHAIN - BRI2, membrane form. {ECO:0000250}. (1|243)
1,266,0,1 CHAIN - BRI2 intracellular domain. {ECO:0000250}. (1|0)
1,266,54,1 TOPO_DOM - Cytoplasmic. {ECO:0000255}. (1|54)
 
unknown-40DPDDVV...
40,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Doskeland, PROBE RAT-leukemia-IPC81-IDA-AD direct yes 0.05 (MASCOT score)
 

Protein C-Termini [export]

...TLICS0-unknown
0,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,266,0,1 CHAIN - BRI2 intracellular domain. {ECO:0000250}. (1|0)
 
...GIQKR243-unknown
243,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

243,266,243,1 CHAIN - BRI2, membrane form. {ECO:0000250}. (1|243)
243,266,243,0 CHAIN - BRI2C, soluble form. {ECO:0000250}. (0|243)
 
...TLICS266-unknown
266,266

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

266,266,266,1 CHAIN - Integral membrane protein 2B. (1|266)
266,266,266,244 PEPTIDE - Bri23 peptide. {ECO:0000250}. (244|266)
266,266,266,76 TOPO_DOM - Lumenal. {ECO:0000255}. (76|266)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • MASCOT score

Experimental system ?

Certainty of Protease assignment ?

  • unknown
  • IV proteolytic system present and active

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?