Q61602: Transcriptional activator GLI3 (Mouse)

Protein names
  • Transcriptional activator GLI3
  • GLI3 form of 190 kDa Short=GLI3-190
  • GLI3 full length protein Short=GLI3FL
  • GLI3
Gene names Gli3
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 13

Sequence

        10         20         30         40         50         60 
MEAQAHSSTA TERKKAENSI GKCPTRTDVS EKAVASSTTS NEDESPGQIY HRERRNAITM 
        70         80         90        100        110        120 
QPQSVQGLNK ISEEPSTSSD ERASLIKKEI HGSLPHLAEP SLPYRGTVFA MDPRNGYMEP 
       130        140        150        160        170        180 
HYHPPHLFPA FHPPVPIDAR HHEGRYHYDP SPIPPLHVPS ALSSSPTYPD LPFIRISPHR 
       190        200        210        220        230        240 
NPTAASESPF SPPHPYINPY MDYIRSLHSS PSLSMISAAR GLSPTDAPHA GVSPAEYYHQ 
       250        260        270        280        290        300 
MALLTGQRSP YADILPSAAT AGAGAIHMEY LHAMDSTRFP SPRLSARPSR KRTLSISPLS 
       310        320        330        340        350        360 
DHSFDLQTMI RTSPNSLVTI LNNSRSSSSA SGSYGHLSAS AISPALSFTY PSAPVSLHMH 
       370        380        390        400        410        420 
QQILSRQQSL GSAFGHSPPL IHPAPTFPTQ RPIPGIPTVL NPVQVSSGPS ESSQSKPTSE 
       430        440        450        460        470        480 
SAVSSTGDPM HNKRSKIKPD EDLPSPGSRG QQEQPEGTTL VKEEADKDES KQEPEVIYET 
       490        500        510        520        530        540 
NCHWEGCTRE FDTQDQLVHH INNDHIHGEK KEFVCRWLDC SREQKPFKAQ YMLVVHMRRH 
       550        560        570        580        590        600 
TGEKPHKCTF EGCTKAYSRL ENLKTHLRSH TGEKPYVCEH EGCNKAFSNA SDRAKHQNRT 
       610        620        630        640        650        660 
HSNEKPYVCK IPGCTKRYTD PSSLRKHVKT VHGPEAHVTK KQRGDMHPRP PPPRDSGSHS 
       670        680        690        700        710        720 
QSRSPGRPTQ GAFGEQKELS NTTSKREECL QVKTVKAEKP MTSQPSPGGQ SSCSSQQSPI 
       730        740        750        760        770        780 
SNYSNSGLEL PLTDGGSVAD LSAIDETPIM DSTISTATTA LALQARRNPA GTKWMEHIKL 
       790        800        810        820        830        840 
ERLKQVNGMF PRLNPILPSK APAVSPLIGN GTQSNNNYSS GGPGTLLPSR SDLSGVDFTV 
       850        860        870        880        890        900 
LNTLNRRDSN TSTISSAYLS SRRSSGISPC FSSRRSSEAS QAEGRPQNVS VADSYDPIST 
       910        920        930        940        950        960 
DASRRSSEAS QGDGLPSLLS LTPVQQYRLK AKYAAATGGP PPTPLPHMER LSLKTKMALL 
       970        980        990       1000       1010       1020 
GEGRDSGVTL PPVHPPRRCS DGGGHTYRGR HLMPHDALAN SVRRASDPVR TVSENMSLAR 
      1030       1040       1050       1060       1070       1080 
VQRFSSLNSF NPPNLPPSVE KRSLVLQNYT RQESSQPRYF QASPCPPSIT ENVALEALTM 
      1090       1100       1110       1120       1130       1140 
DADANLNDED LLPDDVVQYL NSQNQTGYGQ QLQSGISEDS KVAHEPEDLD LAGLPDSHVG 
      1150       1160       1170       1180       1190       1200 
QEYPALEQPC SEGSKTDLPI QWNEVSSGTS DLSSSKLKCG QQRPSAQQPR GFGLYNNMVV 
      1210       1220       1230       1240       1250       1260 
HPHNLWKVGT GPAGGYQTLG ENSSTYNGPE HFAIHSGDGL GTNGNTFHEQ PFKTQQYGSQ 
      1270       1280       1290       1300       1310       1320 
LNRQPLTSSA LDHACGTGIQ GSKLKGNSLQ ENGGLLDFSL SVAPNELAGN TVNGMQTQDQ 
      1330       1340       1350       1360       1370       1380 
MGQGYIAHQL LSGSMQHQGP SRPGQQVLGQ VGATSHINIY QGTESCLPGT QDNSSQPSSM 
      1390       1400       1410       1420       1430       1440 
AAIRGYQPCA SYGGNRRQAM PRGNLTLQQG QLSDMSQSSR VNSIKMEAQG QSQQLCSTVQ 
      1450       1460       1470       1480       1490       1500 
NYSGQFYDQT MGFSQQDRKA GSFSLSDANC LLQGNGTENS ELLSPGANQV TSTVDSFESH 
      1510       1520       1530       1540       1550       1560 
DLEGVQIDFD AIIDDGDHTS LMSGALSPSI IQNLSHSSSR LTTPRASLPF PSLSMGTTNM 
      1570       1580    
AIGDMSSLLT SLAEESKFLA VMQ

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:
 
 
 
N-termini:

N
 
C-termini:

CCC
 
Binding & active sites:
     
 
Sequence variations:
       
 
Topology:
    
 
Modifications:
        
 
acetylation-1MEAQAH...
1,1583

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,1583,1,1 MOD_RES - N-acetylmethionine (By similarity). (1|1)
1,1583,1583,1 CHAIN - Transcriptional activator GLI3. (1|1583)
1,1583,0,1 CHAIN - Transcriptional repressor GLI3R. (1|0)
 

Protein C-Termini [export]

...LAVMQ0-unknown
0,1583

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,1583,0,1 CHAIN - Transcriptional repressor GLI3R. (1|0)
 
...DRAKH596-unknown
596,1583

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000115989 unknown unknown (unknown)
 
...LAVMQ1583-unknown
1583,1583

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1583,1583,1583,1 CHAIN - Transcriptional activator GLI3. (1|1583)
 
Filter by evidence: ?

Directness ?

  • unknown

Physiological relevance ?

  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?