Q68CJ9: Cyclic AMP-responsive element-binding protein 3-like protein 3 (Human)

Protein names
  • Cyclic AMP-responsive element-binding protein 3-like protein 3 (cAMP-responsive element-binding protein 3-like protein 3)
  • Transcription factor CREB-H (cAMP-responsive element-binding protein 3-like protein 3)
  • CR3L3
Gene names CREB3L3 (CREBH)
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 19

Isoforms

  • Isoform 2 of Cyclic AMP-responsive element-binding protein 3-like protein 3 (Q68CJ9-2): sequence view | extended view
  • Isoform 3 of Cyclic AMP-responsive element-binding protein 3-like protein 3 (Q68CJ9-4): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MNTDLAAGKM ASAACSMDPI DSFELLDLLF DRQDGILRHV ELGEGWGHVK DQQVLPNPDS 
        70         80         90        100        110        120 
DDFLSSILGS GDSLPSSPLW SPEGSDSGIS EDLPSDPQDT PPRSGPATSP AGCHPAQPGK 
       130        140        150        160        170        180 
GPCLSYHPGN SCSTTTPGPV IQVPEASVTI DLEMWSPGGR ICAEKPADPV DLSPRCNLTV 
       190        200        210        220        230        240 
KDLLLSGSSG DLQQHHLGAS YLLRPGAGHC QELVLTEDEK KLLAKEGITL PTQLPLTKYE 
       250        260        270        280        290        300 
ERVLKKIRRK IRNKQSAQES RKKKKEYIDG LETRMSACTA QNQELQRKVL HLEKQNLSLL 
       310        320        330        340        350        360 
EQLKKLQAIV VQSTSKSAQT GTCVAVLLLS FALIILPSIS PFGPNKTESP GDFAPVRVFS 
       370        380        390        400        410        420 
RTLHNDAASR VAADAVPGSE APGPRPEADT TREESPGSPG ADWGFQDTAN LTNSTEELDN 
       430        440        450        460    
ATLVLRNATE GLGQVALLDW VAPGPSTGSG RAGLEAAGDE L

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
Chains:
 
 
 
N-termini:

NNN
 
C-termini:

CCC
 
Cleavage sites:
 
 
Features:
 
   
 
Sequence variations:
    
 
Topology:
   
 
(SRTLH(364)|(365)NDAAS)
364,461

Membrane-bound transcription factor site-1 protease (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Seidah NG Pasquato A et al.:The proprotein convertase SKI-1... (S08.063) unknown yes

Targeted features: ?

364,461,461,344 TOPO_DOM - Lumenal (Potential). (344|461)
364,461,461,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 3. (1|461)

Affected feature boundaries: ?

364,461,364,363 SITE - Cleavage; by PS1 (By similarity). (363|364)
 
unknown-1MNTDLA...
1,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt71637 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt71638 indirect unknown (unknown)

Affected feature boundaries: ?

1,461,322,1 TOPO_DOM - Cytoplasmic (Potential). (1|322)
1,461,461,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 3. (1|461)
1,461,0,1 CHAIN - Processed cyclic AMP-responsive element- binding protein 3-like protein 3. (1|0)
 
unknown-10MASAAC...
10,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000252587 unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt194876 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt194877 indirect unknown (unknown)
 
unknown-365NDAASR...
365,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC16836 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt151257 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt151286 indirect unknown (unknown)
 

Protein C-Termini [export]

...AGDEL0-unknown
0,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,461,0,1 CHAIN - Processed cyclic AMP-responsive element- binding protein 3-like protein 3. (1|0)
 
...SRTLH364-unknown
364,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC16836 indirect unknown (unknown)

Affected feature boundaries: ?

364,461,364,363 SITE - Cleavage; by PS1 (By similarity). (363|364)
 
...AGDEL461-unknown
461,461

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt67256 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt67255 indirect unknown (unknown)

Affected feature boundaries: ?

461,461,461,344 TOPO_DOM - Lumenal (Potential). (344|461)
461,461,461,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 3. (1|461)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?