Q86WC4: Osteopetrosis-associated transmembrane protein 1 (Human)

Protein names
  • Osteopetrosis-associated transmembrane protein 1
  • Chloride channel 7 beta subunit
  • OSTM1
Gene names OSTM1 (GL)
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 6

Sequence

        10         20         30         40         50         60 
MEPGPTAAQR RCSLPPWLPL GLLLWSGLAL GALPFGSSPH RVFHDLLSEQ QLLEVEDLSL 
        70         80         90        100        110        120 
SLLQGGGLGP LSLPPDLPDL DPECRELLLD FANSSAELTG CLVRSARPVR LCQTCYPLFQ 
       130        140        150        160        170        180 
QVVSKMDNIS RAAGNTSESQ SCARSLLMAD RMQIVVILSE FFNTTWQEAN CANCLTNNSE 
       190        200        210        220        230        240 
ELSNSTVYFL NLFNHTLTCF EHNLQGNAHS LLQTKNYSEV CKNCREAYKT LSSLYSEMQK 
       250        260        270        280        290        300 
MNELENKAEP GTHLCIDVED AMNITRKLWS RTFNCSVPCS DTVPVIAVSV FILFLPVVFY 
       310        320        330    
LSSFLHSEQK KRKLILPKRL KSSTSFANIQ ENSN

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
Chains:
 
 
N-termini:
N
NN
 
C-termini:
CC
C
 
Features:
 
 
Sequence variations:
  
 
Topology:
   
 
Modifications:
   
 
unknown-32ALPFGS...
32,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)
Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)

Affected feature boundaries: ?

32,334,334,32 CHAIN - Osteopetrosis-associated transmembrane protein 1. (32|334)
32,334,284,32 TOPO_DOM - Lumenal (Potential). (32|284)
 
unknown-32ALPFGS...
32,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Wells DB_Untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_DB_Doxo direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_Etoposide direct yes 0.02 (ProteinProspector)
Wells Jurkat_untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_staurotrail direct yes 0.02 (ProteinProspector)

Affected feature boundaries: ?

32,334,334,32 CHAIN - Osteopetrosis-associated transmembrane protein 1. (32|334)
32,334,284,32 TOPO_DOM - Lumenal (Potential). (32|284)
 
unknown-148MADRMQ...
148,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000398556 unknown unknown (unknown)
 

Protein C-Termini [export]

...ILPKR319-unknown
319,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSP00000398556 unknown unknown (unknown)
 
...QENSN334-unknown
334,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Gevaert K. Van Damme P et al.: Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)

Affected feature boundaries: ?

334,334,334,32 CHAIN - Osteopetrosis-associated transmembrane protein 1. (32|334)
334,334,334,306 TOPO_DOM - Cytoplasmic (Potential). (306|334)
 
...QENSN334-unknown
334,334

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Gevaert K. Van Damme P et al.: Complementary positional proteomics for screening substrates... direct yes 0.0 (unknown)

Affected feature boundaries: ?

334,334,334,32 CHAIN - Osteopetrosis-associated transmembrane protein 1. (32|334)
334,334,334,306 TOPO_DOM - Cytoplasmic (Potential). (306|334)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • ProteinProspector

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?