Q91YR1: Twinfilin-1 (Mouse)

Protein names
  • Twinfilin-1
  • Protein A6
  • TWF1
Gene names Twf1 (Ptk9)
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 15

Sequence

        10         20         30         40         50         60 
MSHQTGIQAS EDVKEIFARA RNGKYRLLKI SIENEQLVVG SCSPPSDSWE QDYDSFVLPL 
        70         80         90        100        110        120 
LEDKQPCYVL FRLDSQNAQG YEWIFIAWSP DHSHVRQKML YAATRATLKK EFGGGHIKDE 
       130        140        150        160        170        180 
VFGTVKEDVS LHGYKKYLLS QSSPAPLTAA EEELRQIKIN EVQTDVSVDT KHQTLQGVAF 
       190        200        210        220        230        240 
PISRDAFQAL EKLSKKQLNY VQLEIDIKNE TIILANTENT ELRDLPKRIP KDSARYHFFL 
       250        260        270        280        290        300 
YKHSHEGDYL ESVVFIYSMP GYTCSIRERM LYSSCKSPLL EIVERQLQMD VIRKIEIDNG 
       310        320        330        340        350    
DELTADFLYD EVHPKQHAHK QSFAKPKGPA GKRGIRRLIR GPAEAEATTD 

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
Chains:
 
 
N-termini:

N
N
NNNNNN
 
C-termini:
CCCCC
 
Cleavage sites:
  
  
 
Features:
   
 
Sequence variations:
  
 
Modifications:
    
 
(SHQTG(6)|(7)IQASE)
6,350

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

6,350,139,2 DOMAIN - ADF-H 1. (2|139)
6,350,350,2 CHAIN - Twinfilin-1. (2|350)
 
(SSPAP(146)|(147)LTAAE)
146,350

Matrix metalloproteinase-9 (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

Targeted features: ?

146,350,350,2 CHAIN - Twinfilin-1. (2|350)
 
(TKHQT(174)|(175)LQGVA)
174,350

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM auf dem Keller U et al.:A statistics-based platform for... (M10.003) unknown none

Targeted features: ?

174,350,350,2 CHAIN - Twinfilin-1. (2|350)

Affected feature boundaries: ?

174,350,313,175 DOMAIN - ADF-H 2. (175|313)
 
unknown-1MSHQTG...
1,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from similarity UniProtKB inferred from uniprot (by similarity) unknown unknown (unknown)

Affected feature boundaries: ?

1,350,1,1 INIT_MET - Removed (By similarity). (1|1)
 
acetylation-2SHQTGI...
2,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
Overall CM. Kleifeldt O. et al.: Isotopic labeling of terminal amines in complex samples identifies... direct likely 0.0 (unknown)
Overall CM. Prudova A.: Multiplex N-terminome analysis of MMP-2 and MMP-9... direct likely 0.0 (unknown)

Affected feature boundaries: ?

2,350,2,2 MOD_RES - N-acetylserine (By similarity). (2|2)
2,350,139,2 DOMAIN - ADF-H 1. (2|139)
2,350,350,2 CHAIN - Twinfilin-1. (2|350)
 
unknown-7IQASED...
7,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34143 indirect unknown (unknown)
 
unknown-54DSFVLP...
54,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
 
unknown-68YVLFRL...
68,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation TISdb inferred from TISdb unknown unknown (unknown)
 
unknown-147LTAAEE...
147,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34635 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC34144 indirect unknown (unknown)
 
unknown-166VSVDTK...
166,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Overall CM. auf dem Keller U.: A statistics-based platform for quantitative N-terminome... direct likely 0.0 (unknown)
 
unknown-175LQGVAF...
175,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34145 indirect unknown (unknown)

Affected feature boundaries: ?

175,350,313,175 DOMAIN - ADF-H 2. (175|313)
 

Protein C-Termini [export]

...SHQTG6-unknown
6,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34143 indirect unknown (unknown)
 
...KYLLS140-unknown
140,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation Ensembl inferred from ensembl protein ENSMUSP00000119302 unknown unknown (unknown)
 
...SSPAP146-unknown
146,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34635 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC34144 indirect unknown (unknown)
 
...TKHQT174-unknown
174,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34145 indirect unknown (unknown)
 
...EATTD350-unknown
350,350

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

350,350,350,2 CHAIN - Twinfilin-1. (2|350)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct
  • indirect

Physiological relevance ?

  • none
  • unknown
  • likely

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?