Q969S9: Ribosome-releasing factor 2, mitochondrial (Human)

Protein names
  • Ribosome-releasing factor 2, mitochondrial (RRF2mt)
  • Elongation factor G 2, mitochondrial Short=EF-G2mt Short=mEF-G 2 (RRF2mt)
  • Elongation factor G2 Short=hEFG2 (RRF2mt)
  • RRF2M
Gene names GFM2
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 5

Isoforms

  • Isoform 2 of Ribosome-releasing factor 2, mitochondrial (Q969S9-2): sequence view | extended view
  • Isoform 3 of Ribosome-releasing factor 2, mitochondrial (Q969S9-3): sequence view | extended view
  • Isoform 4 of Ribosome-releasing factor 2, mitochondrial (Q969S9-4): sequence view | extended view
  • Isoform 5 of Ribosome-releasing factor 2, mitochondrial (Q969S9-5): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MLTNLRIFAM SHQTIPSVYI NNICCYKIRA SLKRLKPHVP LGRNCSSLPG LIGNDIKSLH 
        70         80         90        100        110        120 
SIINPPIAKI RNIGIMAHID AGKTTTTERI LYYSGYTRSL GDVDDGDTVT DFMAQERERG 
       130        140        150        160        170        180 
ITIQSAAVTF DWKGYRVNLI DTPGHVDFTL EVERCLRVLD GAVAVFDASA GVEAQTLTVW 
       190        200        210        220        230        240 
RQADKHNIPR ICFLNKMDKT GASFKYAVES IREKLKAKPL LLQLPIGEAK TFKGVVDVVM 
       250        260        270        280        290        300 
KEKLLWNCNS NDGKDFERKP LLEMNDPELL KETTEARNAL IEQVADLDDE FADLVLEEFS 
       310        320        330        340        350        360 
ENFDLLPAEK LQTAIHRVTL AQTAVPVLCG SALKNKGIQP LLDAVTMYLP SPEERNYEFL 
       370        380        390        400        410        420 
QWYKDDLCAL AFKVLHDKQR GPLVFMRIYS GTIKPQLAIH NINGNCTERI SRLLLPFADQ 
       430        440        450        460        470        480 
HVEIPSLTAG NIALTVGLKH TATGDTIVSS KSSALAAARR AEREGEKKHR QNNEAERLLL 
       490        500        510        520        530        540 
AGVEIPEPVF FCTIEPPSLS KQPDLEHALK CLQREDPSLK VRLDPDSGQT VLCGMGELHI 
       550        560        570        580        590        600 
EIIHDRIKRE YGLETYLGPL QVAYRETILN SVRATDTLDR TLGDKRHLVT VEVEARPIET 
       610        620        630        640        650        660 
SSVMPVIEFE YAESINEGLL KVSQEAIENG IHSACLQGPL LGSPIQDVAI TLHSLTIHPG 
       670        680        690        700        710        720 
TSTTMISACV SRCVQKALKK ADKQVLEPLM NLEVTVARDY LSPVLADLAQ RRGNIQEIQT 
       730        740        750        760        770    
RQDNKVVIGF VPLAEIMGYS TVLRTLTSGS ATFALELSTY QAMNPQDQNT LLNRRSGLT

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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Chains:

 
 
N-termini:

N
NN
N
 
C-termini:
C
 
Features:
 
 
Binding & active sites:
   
 
Sequence variations:
        
  
    
 
unknown-0TMLTNL...
0,779

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,779,779,0 CHAIN - Ribosome-releasing factor 2, mitochondrial. (0|779)
 
unknown-1MLTNLR...
1,779

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt88237 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt88238 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt88239 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt88240 indirect unknown (unknown)

Affected feature boundaries: ?

1,779,0,1 TRANSIT - Mitochondrion (Potential). (1|0)
 
unknown-46SSLPGL...
46,779

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Wells DB_Untreated direct yes 0.02 (ProteinProspector)
Wells THP_untreated direct yes 0.02 (ProteinProspector)
 
unknown-46SSLPGL...
46,779

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt164741 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt164742 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt164743 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt164744 indirect unknown (unknown)
 

Protein C-Termini [export]

...RSGLT779-unknown
779,779

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt83857 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt83855 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt83856 indirect unknown (unknown)

Affected feature boundaries: ?

779,779,779,0 CHAIN - Ribosome-releasing factor 2, mitochondrial. (0|779)
779,779,779,514 VAR_SEQ - Missing (in isoform 5). (514|779)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • ProteinProspector

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?