Q96BA8: Cyclic AMP-responsive element-binding protein 3-like protein 1 (Human)

Protein names
  • Cyclic AMP-responsive element-binding protein 3-like protein 1 (cAMP-responsive element-binding protein 3-like protein 1)
  • Old astrocyte specifically-induced substance Short=OASIS (cAMP-responsive element-binding protein 3-like protein 1)
  • CR3L1
Gene names CREB3L1
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 11

Isoforms

  • Isoform 2 of Cyclic AMP-responsive element-binding protein 3-like protein 1 (Q96BA8-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFTENMEDF SNDLFSSFFD 
        70         80         90        100        110        120 
DPVLDEKSPL LDMELDSPTP GIQAEHSYSL SGDSAPQSPL VPIKMEDTTQ DAEHGAWALG 
       130        140        150        160        170        180 
HKLCSIMVKQ EQSPELPVDP LAAPSAMAAA AAMATTPLLG LSPLSRLPIP HQAPGEMTQL 
       190        200        210        220        230        240 
PVIKAEPLEV NQFLKVTPED LVQMPPTPPS SHGSDSDGSQ SPRSLPPSSP VRPMARSSTA 
       250        260        270        280        290        300 
ISTSPLLTAP HKLQGTSGPL LLTEEEKRTL IAEGYPIPTK LPLTKAEEKA LKRVRRKIKN 
       310        320        330        340        350        360 
KISAQESRRK KKEYVECLEK KVETFTSENN ELWKKVETLE NANRTLLQQL QKLQTLVTNK 
       370        380        390        400        410        420 
ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPEFSSG SQTVKEDPLA ADGVYTASQM 
       430        440        450        460        470        480 
PSRSLLFYDD GAGLWEDGRS TLLPMEPPDG WEINPGGPAE QRPRDHLQHD HLDSTHETTK 
       490        500        510    
YLSEAWPKDG GNGTSPDFSH SKEWFHDRDL GPNTTIKLS

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
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400
500
Chains:
 
 
 
N-termini:

NN
 
C-termini:

CCC
 
Cleavage sites:
 
 
Features:
  
   
 
Sequence variations:
      
 
Topology:
   
 
(SRSLL(426)|(427)FYDDG)
426,519

Membrane-bound transcription factor site-1 protease (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Seidah NG Pasquato A et al.:The proprotein convertase SKI-1... (S08.063) unknown yes

Targeted features: ?

426,519,519,396 TOPO_DOM - Lumenal (Potential). (396|519)
426,519,519,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 1. (1|519)

Affected feature boundaries: ?

426,519,427,426 SITE - Cleavage; by PS1 (By similarity). (426|427)
426,519,426,426 MUTAGEN - L->V: Abolishes proteolytic cleavage by PS1. (426|426)
426,519,426,426 MUTAGEN - L->V: Abolishes proteolytic cleavage by PS1. (426|426)
 
unknown-1MDAVLE...
1,519

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt71633 indirect unknown (unknown)

Affected feature boundaries: ?

1,519,374,1 TOPO_DOM - Cytoplasmic (Potential). (1|374)
1,519,519,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 1. (1|519)
1,519,0,1 CHAIN - Processed cyclic AMP-responsive element- binding protein 3-like protein 1. (1|0)
1,519,60,1 REGION - Required for transcriptional activation. (1|60)
 
unknown-427FYDDGA...
427,519

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC16842 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt150713 indirect unknown (unknown)
 

Protein C-Termini [export]

...TIKLS0-unknown
0,519

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,519,0,1 CHAIN - Processed cyclic AMP-responsive element- binding protein 3-like protein 1. (1|0)
 
...SRSLL426-unknown
426,519

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC16842 indirect unknown (unknown)

Affected feature boundaries: ?

426,519,426,426 MUTAGEN - L->V: Abolishes proteolytic cleavage by PS1. (426|426)
 
...TIKLS519-unknown
519,519

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt67251 indirect unknown (unknown)

Affected feature boundaries: ?

519,519,519,396 TOPO_DOM - Lumenal (Potential). (396|519)
519,519,519,1 CHAIN - Cyclic AMP-responsive element-binding protein 3-like protein 1. (1|519)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?