Q9BW92: Threonine--tRNA ligase, mitochondrial (Human)

Protein names
  • Threonine--tRNA ligase, mitochondrial
  • Threonyl-tRNA synthetase Short=ThrRS
  • Threonyl-tRNA synthetase-like 1
  • SYTM
Gene names TARS2
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 1

Isoforms

  • Isoform 2 of Threonine--tRNA ligase, mitochondrial (Q9BW92-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MALYQRWRCL RLQGLQACRL HTAVVSTPPR WLAERLGLFE ELWAAQVKRL ASMAQKEPRT 
        70         80         90        100        110        120 
IKISLPGGQK IDAVAWNTTP YQLARQISST LADTAVAAQV NGEPYDLERP LETDSDLRFL 
       130        140        150        160        170        180 
TFDSPEGKAV FWHSSTHVLG AAAEQFLGAV LCRGPSTEYG FYHDFFLGKE RTIRGSELPV 
       190        200        210        220        230        240 
LERICQELTA AARPFRRLEA SRDQLRQLFK DNPFKLHLIE EKVTGPTATV YGCGTLVDLC 
       250        260        270        280        290        300 
QGPHLRHTGQ IGGLKLLSNS SSLWRSSGAP ETLQRVSGIS FPTTELLRVW EAWREEAELR 
       310        320        330        340        350        360 
DHRRIGKEQE LFFFHELSPG SCFFLPRGTR VYNALVAFIR AEYAHRGFSE VKTPTLFSTK 
       370        380        390        400        410        420 
LWEQSGHWEH YQEDMFAVQP PGSDRPPSSQ SDDSTRHITD TLALKPMNCP AHCLMFAHRP 
       430        440        450        460        470        480 
RSWRELPLRL ADFGALHRAE ASGGLGGLTR LRCFQQDDAH IFCTTDQLEA EIQSCLDFLR 
       490        500        510        520        530        540 
SVYAVLGFSF RLALSTRPSG FLGDPCLWDQ AEQVLKQALK EFGEPWDLNS GDGAFYGPKI 
       550        560        570        580        590        600 
DVHLHDALGR PHQCGTIQLD FQLPLRFDLQ YKGQAGALER PVLIHRAVLG SVERLLGVLA 
       610        620        630        640        650        660 
ESCGGKWPLW LSPFQVVVIP VGSEQEEYAK EAQQSLRAAG LVSDLDADSG LTLSRRIRRA 
       670        680        690        700        710    
QLAHYNFQFV VGQKEQSKRT VNIRTRDNRR LGEWDLPEAV QRLVELQNTR VPNAEEIF

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
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700
Chains:

 
 
N-termini:

N
NN
N
 
C-termini:
C
 
Features:
 
 
Sequence variations:
 
  
 
Modifications:
 
 
unknown-0FMALYQ...
0,718

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,718,718,0 CHAIN - Threonine--tRNA ligase, mitochondrial. (0|718)
 
unknown-1MALYQR...
1,718

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt91317 indirect unknown (unknown)

Affected feature boundaries: ?

1,718,0,1 TRANSIT - Mitochondrion (Potential). (1|0)
 
unknown-20LHTAVV...
20,718

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt160339 indirect unknown (unknown)
 
unknown-20LHTAVV...
20,718

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Wells apoptotic_DB_Doxo direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_bortezomib direct yes 0.02 (ProteinProspector)
Wells Jurkat_untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_staurotrail direct yes 0.02 (ProteinProspector)
Wells apoptotic_MM1s_bort direct yes 0.02 (ProteinProspector)
Wells MM1SDBJurkat_Untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_MM1SDBJurkat_Mix direct yes 0.02 (ProteinProspector)
Wells apoptotic_RPMI_Dox direct yes 0.02 (ProteinProspector)
Wells apoptosis_U266_bortezomib_induced direct yes 0.02 (ProteinProspector)
 

Protein C-Termini [export]

...AEEIF718-unknown
718,718

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt86935 indirect unknown (unknown)

Affected feature boundaries: ?

718,718,718,0 CHAIN - Threonine--tRNA ligase, mitochondrial. (0|718)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • ProteinProspector

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?