Q9CQV8: 14-3-3 protein beta/alpha (Mouse)

Protein names
  • 14-3-3 protein beta/alpha
  • Protein kinase C inhibitor protein 1 Short=KCIP-1
  • 1433B
Gene names Ywhab
Organism Mus musculus
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 2

Isoforms

  • Isoform Short of 14-3-3 protein beta/alpha (Q9CQV8-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS 
        70         80         90        100        110        120 
WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLILN ATQAESKVFY 
       130        140        150        160        170        180 
LKMKGDYFRY LSEVASGENK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY 
       190        200        210        220        230        240 
YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD 
   
AGEGEN

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
Chains:
 
 
 
N-termini:

N
N
NNNN
N
 
C-termini:
CCC
CC
 
Cleavage sites:
   
  
 
 
Features:
   
 
Sequence variations:
    
 
Modifications:
        
 
(DKSEL(8)|(9)VQKAK)
8,246

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433B_MOUSE @8 unknown yes

Targeted features: ?

8,246,17,5 HELIX - (5|17)
8,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
8,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
(DMAAA(27)|(28)MKAVT)
27,246

72 kDa type IV collagenase (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Overall CM Prudova A et al.:Multiplex N-terminome analysis ... (M10.004) unknown none

Targeted features: ?

27,246,33,21 HELIX - (21|33)
27,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
27,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
(EERNL(45)|(46)LSVAY)
45,246

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433B_MOUSE @45 unknown yes

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Zornig M Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009) unknown yes

Targeted features: ?

45,246,68,40 HELIX - (40|68)
45,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
45,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
(ERNLL(46)|(47)SVAYK)
46,246

Cathepsin E (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Merops CATE_MOUSE -> 1433B_MOUSE @46 unknown yes

Cathepsin D (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Zornig M Melzer IM et al.:The Apaf-1-binding protein Aven... (A01.009) unknown yes

Targeted features: ?

46,246,68,40 HELIX - (40|68)
46,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
46,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
acetylation-1MTMDKS...
1,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

1,246,2,1 VAR_SEQ - Missing (in isoform Short). (1|2)
1,246,1,1 INIT_MET - Removed; alternate (By similarity). (1|1)
1,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
1,246,1,1 MOD_RES - N-acetylmethionine (By similarity). (1|1)
 
acetylation-2TMDKSE...
2,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from similarity UniProtKB inferred from uniprot (by similarity) unknown unknown (unknown)
Kleifeldt O. et al.: N-terminome analysis of bronchoalveolar lavage fluids collected from... unknown unknown (unknown)

Affected feature boundaries: ?

2,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
2,246,2,2 MOD_RES - N-acetylthreonine; in 14-3-3 protein beta/alpha, N-terminally processed (By similarity). (2|2)
 
unknown-3MDKSEL...
3,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt65719 indirect unknown (unknown)
 
unknown-9VQKAKL...
9,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31014 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt194824 indirect unknown (unknown)
 
unknown-28MKAVTE...
28,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34200 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt137279 indirect unknown (unknown)
 
unknown-46LSVAYK...
46,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31015 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29329 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt138648 indirect unknown (unknown)
 
unknown-47SVAYKN...
47,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31017 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29331 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt138713 indirect unknown (unknown)
 

Protein C-Termini [export]

...DKSEL8-unknown
8,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31014 indirect unknown (unknown)
 
...DMAAA27-unknown
27,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC34200 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt120211 indirect unknown (unknown)
 
...EERNL45-unknown
45,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31015 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29329 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt121701 indirect unknown (unknown)
 
...ERNLL46-unknown
46,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from cleavage TopFIND Inferred from cleavage TC31017 indirect unknown (unknown)
inferred from cleavage TopFIND Inferred from cleavage TC29331 indirect unknown (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt121767 indirect unknown (unknown)
 
...GEGEN246-unknown
246,246

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TCt61337 indirect unknown (unknown)

Affected feature boundaries: ?

246,246,246,1 CHAIN - 14-3-3 protein beta/alpha. (1|246)
246,246,246,2 CHAIN - 14-3-3 protein beta/alpha, N-terminally processed. (2|246)
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • none
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?