Q9NZJ6: Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial (Human)

Protein names
  • Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial
  • 2-polyprenyl-6-hydroxyphenol methylase EC=2.1.1.222
  • 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase Short=DHHB methyltransferase Short=DHHB-MT Short=DHHB-MTase
  • 3-demethylubiquinone-10 3-methyltransferase EC=2.1.1.64
  • Dihydroxyhexaprenylbenzoate methyltransferase
  • COQ3
Gene names COQ3
Organism Homo sapiens
Protease Family (Not Available)
Protease ID (Not Available)
Chromosome 6

Sequence

        10         20         30         40         50         60 
MWSGRKLGSS GGWFLRVLGP GGCNTKAARP LISSAVYVKN QLSGTLQIKP GVFNEYRTIW 
        70         80         90        100        110        120 
FKSYRTIFSC LNRIKSFRYP WARLYSTSQT TVDSGEVKTF LALAHKWWDE QGVYAPLHSM 
       130        140        150        160        170        180 
NDLRVPFIRD NLLKTIPNHQ PGKPLLGMKI LDVGCGGGLL TEPLGRLGAS VIGIDPVDEN 
       190        200        210        220        230        240 
IKTAQCHKSF DPVLDKRIEY RVCSLEEIVE ETAETFDAVV ASEVVEHVID LETFLQCCCQ 
       250        260        270        280        290        300 
VLKPGGSLFI TTINKTQLSY ALGIVFSEQI ASIVPKGTHT WEKFVSPETL ESILESNGLS 
       310        320        330        340        350        360 
VQTVVGMLYN PFSGYWHWSE NTSLNYAAYA VKSRVQEHPA SAEFVLKGET EELQANACTN 
   
PAVHEKLKK

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
Chains:

 
 
N-termini:

NN
N
 
C-termini:
C
 
Features:
 
 
Sequence variations:
       
 
Modifications:
   
 
unknown-0KMWSGR...
0,369

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

0,369,369,0 CHAIN - Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial. (0|369)
 
unknown-86STSQTT...
86,369

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Mahrus S. et al.: nonapototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)
Mahrus S. et al.: apototic Jurkat cells, Global Sequencing of Proteolytic Cleavage... unknown unknown (unknown)
 
unknown-86STSQTT...
86,369

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
Wells DB_Untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_DB_Doxo direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_Etoposide direct yes 0.02 (ProteinProspector)
Wells Jurkat_untreated direct yes 0.02 (ProteinProspector)
Wells apoptotic_Jurkat_staurotrail direct yes 0.02 (ProteinProspector)
Wells apoptotic_MM1s_bort direct yes 0.02 (ProteinProspector)
Wells apoptotic_MM1SDBJurkat_Mix direct yes 0.02 (ProteinProspector)
Wells apoptotic_RPMI_Dox direct yes 0.02 (ProteinProspector)
Wells THP_untreated direct yes 0.02 (ProteinProspector)
Wells apoptosis_U266_bortezomib_induced direct yes 0.02 (ProteinProspector)
 

Protein C-Termini [export]

...EKLKK369-unknown
369,369

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

369,369,369,0 CHAIN - Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial. (0|369)
 
Filter by evidence: ?

Directness ?

  • unknown
  • direct

Physiological relevance ?

  • unknown
  • yes

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown
  • ProteinProspector

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?