Q9ULZ9: Matrix metalloproteinase-17 (Human)

Protein names
  • Matrix metalloproteinase-17 (MMP-17)
  • Membrane-type matrix metalloproteinase 4 Short=MT-MMP 4 Short=MTMMP4 (MMP-17)
  • Membrane-type-4 matrix metalloproteinase Short=MT4-MMP Short=MT4MMP (MMP-17)
  • MMP17
Gene names MMP17 (MT4MMP)
Organism Homo sapiens
Protease Family M10 (MEROPS)
Protease ID M10.017 (MEROPS)
Chromosome 12

Isoforms

  • Isoform Short of Matrix metalloproteinase-17 (Q9ULZ9-2): sequence view | extended view

Sequence

        10         20         30         40         50         60 
MRRRAARGPG PPPPGPGLSR LPLPLLLLLA LGTRGGCAAP APAPRAEDLS LGVEWLSRFG 
        70         80         90        100        110        120 
YLPPADPTTG QLQTQEELSK AITAMQQFGG LEATGILDEA TLALMKTPRC SLPDLPVLTQ 
       130        140        150        160        170        180 
ARRRRQAPAP TKWNKRNLSW RVRTFPRDSP LGHDTVRALM YYALKVWSDI APLNFHEVAG 
       190        200        210        220        230        240 
SAADIQIDFS KADHNDGYPF DGPGGTVAHA FFPGHHHTAG DTHFDDDEAW TFRSSDAHGM 
       250        260        270        280        290        300 
DLFAVAVHEF GHAIGLSHVA AAHSIMRPYY QGPVGDPLRY GLPYEDKVRV WQLYGVRESV 
       310        320        330        340        350        360 
SPTAQPEEPP LLPEPPDNRS SAPPRKDVPH RCSTHFDAVA QIRGEAFFFK GKYFWRLTRD 
       370        380        390        400        410        420 
RHLVSLQPAQ MHRFWRGLPL HLDSVDAVYE RTSDHKIVFF KGDRYWVFKD NNVEEGYPRP 
       430        440        450        460        470        480 
VSDFSLPPGG IDAAFSWAHN DRTYFFKDQL YWRYDDHTRH MDPGYPAQSP LWRGVPSTLD 
       490        500        510        520        530        540 
DAMRWSDGAS YFFRGQEYWK VLDGELEVAP GYPQSTARDW LVCGDSQADG SVAAGVDAAE 
       550        560        570        580        590        600 
GPRAPPGQHD QSRSEDGYEV CSCTSGASSP PGAPGPLVAA TMLLLLPPLS PGALWTAAQA 
   
LTL

Annotation ?

Network neighborhood
[show protein-protein interactions]
 
100
200
300
400
500
600
Chains:
 
 
N-termini:
NNN
 
C-termini:
CC
 
Features:
  
  
 
Binding & active sites:
     
 
Sequence variations:
 
  
 
Topology:
    
 
Modifications:
 
 
unknown-36GCAAPA...
36,603

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

36,603,125,36 PROPEP - By similarity. (36|125)
 
unknown-85MQQFGG...
85,603

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TNt81287 indirect unknown (unknown)
 
unknown-126QAPAPT...
126,603

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)
inferred from isoform by sequence similarity TopFIND inferred from TNt115913 indirect unknown (unknown)

Affected feature boundaries: ?

126,603,565,126 CHAIN - Matrix metalloproteinase-17. (126|565)
 

Protein C-Termini [export]

...CSCTS565-unknown
565,603

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from electronic annotation UniProtKB inferred from uniprot unknown unknown 0.0 (unknown)

Affected feature boundaries: ?

565,603,565,126 CHAIN - Matrix metalloproteinase-17. (126|565)
565,603,565,565 LIPID - GPI-anchor amidated serine (Potential). (565|565)
 
...QALTL603-unknown
603,603

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance Confidence
inferred from isoform by sequence similarity TopFIND inferred from TCt76905 indirect unknown (unknown)

Affected feature boundaries: ?

603,603,603,566 PROPEP - Removed in mature form (Potential). (566|603)
 
75 (PLAQ.|.AVRS)
75,233

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Murphy G Amour A et al.:The enzymatic activity of ADAM8... (M12.210) unknown yes
 
151 (LPVE.|.NRLY)
151,208

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Murphy G Amour A et al.:The enzymatic activity of ADAM8... (M12.210) unknown yes
 
153 (VENR.|.LYTY)
153,208

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Murphy G Amour A et al.:The enzymatic activity of ADAM8... (M12.210) unknown yes
 
554 ()
554,639

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
556 ()
556,639

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
581 (SALT.|.FREE)
581,837

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Sandy JD Gao G et al.:ADAMTS4 (aggrecanase-1) activat... (M10.017) unknown yes
 
694 (SFRK.|.FRYG)
694,837

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Sandy JD Gao G et al.:ADAMTS4 (aggrecanase-1) activat... (M10.017) unknown yes
 
592 ()
592,677

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
594 ()
594,677

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
610 ()
610,695

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
612 ()
612,695

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
611 ()
611,696

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
613 ()
613,696

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
629 ()
629,714

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
631 ()
631,714

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
648 ()
648,733

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
650 ()
650,733

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
661 ()
661,746

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
663 ()
663,746

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
666 ()
666,751

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
668 ()
668,751

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
667 ()
667,752

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21674 indirect unknown
 
669 ()
669,752

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from isoform by sequence similarity TopFIND inferred from TC21684 indirect unknown
 
685 (EVHH.|.QKLV)
685,770

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Murphy G Amour A et al.:The enzymatic activity of ADAM8... (M12.210) unknown yes
 
687 (HHQK.|.LVFF)
687,770

Evidence: (more...)

Evidence ? Source (database) ? Source (laboratory) ? Name ? Directness of identification ? Phys Relevance
inferred from experiment MEROPS Murphy G Amour A et al.:The enzymatic activity of ADAM8... (M12.210) unknown yes
 
Filter by evidence: ?

Directness ?

  • unknown
  • indirect

Physiological relevance ?

  • yes
  • unknown

Evidencecode ?

Method ?

Perturbation ?

Confidence greater than?

  • unknown

Experimental system ?

Certainty of Protease assignment ?

  • unknown

Evidencecode ?

Tissue distribution ?

Specific evidence ?

Derived from database?

Laboratory ?